Evidence map›Paper›PMID 40764865›Full record

ArticleClinical oral investigations2025

Association of psychosis and oral health: case-control study.

Uta Christine Wölfle, Franziska Beck, Nils Werner, Vinay Pitchika, Katrin Heck, Matthias Folwaczny, Falk Schwendicke, Emanuel Boudriot, Sophie-Kathrin Greiner, Alkomiet Hasan and 3 more

Abstract read
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Uta Christine WölfleDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany. uta.woelfle@med.uni-muenchen.de.
Franziska BeckDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Nils WernerDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Vinay PitchikaDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Katrin HeckDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Matthias FolwacznyDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Falk SchwendickeDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.
Emanuel BoudriotDepartment of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Sophie-Kathrin GreinerDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.
Alkomiet HasanDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Lisa Löhrs *Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Caspar Victor Bumm *Department of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Goethestraße 70, Munich, 80336, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRoughly one in eight individuals presents with psychiatric disorders which were proposed to significantly affect oral health. This study compared oral health of 112 patients (mean 28 years), 31 with schizophrenia spectrum disorders (SSD) or 33 with major depression/bipolar disorders (MDD/BD) to 52 healthy controls (HCG). MATERIALS AND

methodsOral health parameters, including caries experience (decayed-missed-filled teeth/surfaces-index DMFT/DMFS), the presence of plaque (plaque-index PI) and periodontal health (bleeding on probing BOP, periodontal probing depths PPD%), were evaluated by examiners blinded to psychiatric diagnoses. Descriptive statistics summarized demographic and clinical data. Group differences and associations with dental outcomes were analyzed using Chi-square or Mann-Whitney-U tests. Logistic regression identified predictors of oral health.

resultsPatients with SSD or MDD/BD resented with significantly oorer oral health than HCG regarding DMFT (SSD = 9; MDD/BD = 10; HCG = 2), DMFS (SSD = 10; MDD/BD = 12; HCG = 1), PI (SSD = 2; MDD/BD = 2; HCG = 1), BOP (SSD = 20%; MDD/BD = 17%; HCG = 3)% and PPD% (SSD = 1%; MDD/BD = 0%; HCG = 0%) and smoked more often. Differences regarding dental anxiety were not significant (p = 0.112). Subgroup analysis showed no differences between SSD and MDD/BD.

conclusionsSSD and MDD/BD and smoking are key contributors to poor dental health shown by significantly worse DMFT, DMFS and PI, BOP. Probably this might additionally be enhanced by concomitant medication, with multiple psychiatric medication being associated with poorer oral health regarding DMFT, PI and BOP. CLINICAL RELEVANCE: Routine dental care and personalized oral hygiene training to address disease-specific risks are desirable for individuals with SSD or MDD/BD.

Indexed as

Oral HealthPsychotic DisordersAdultCase-Control StudiesDental CariesDMF IndexFemaleHumansMaleMiddle AgedPeriodontal IndexSchizophreniaDental cariesHolistic healthOral diagnosisPsychopharmacologyPsychotic disordersSchizophrenia

Identifiers

PMID40764865
PMCPMC12325445

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.