Evidence map›Paper›PMID 40764840›Full record

ArticleEuropean journal of applied physiology2026

Substituting sitting with standing and walking in free-living conditions improves daily glucose concentrations in South Asian adults living with overweight/obesity.

Kamalesh C Dey, Julia K Zakrzewski-Fruer, Lindsey R Smith, Rebecca L Jones, Benjamin D Maylor, Thomas E Yates, Daniel P Bailey

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04645875 (Substituting Sitting With Standing and Walking in Free-living Conditions Improves Daily Glucose Concentrations in South Asian Adults Living With Overweight/Obesity), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04645875 nacompletednot on this map

Substituting Sitting With Standing and Walking in Free-living Conditions Improves Daily Glucose Concentrations in South Asian Adults Living With Overweight/Obesity

TypeinterventionalSponsorUniversity of BedfordshireRan2020 to 2021Enrolled18ConditionsCardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Type 2 DiabetesArmsSIT regimen, SITless regimen
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kamalesh C DeyInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK.ORCID http://orcid.org/0000-0003-3199-5410
Julia K Zakrzewski-FruerInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK. Julia.Fruer@beds.ac.uk.
Lindsey R SmithInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK.
Rebecca L JonesInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK.ORCID http://orcid.org/0000-0001-9657-9448
Benjamin D MaylorInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK.ORCID http://orcid.org/0000-0002-4503-0479
Thomas E YatesDiabetes Research Centre, University of Leicester, Leicester, LE5 4PW, UK.
Daniel P BaileyInstitute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK. daniel.bailey@brunel.ac.uk.ORCID http://orcid.org/0000-0003-3772-630X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControlled laboratory studies have demonstrated that breaking up sitting can reduce postprandial glucose in South Asian adults. This study examined the effects of substituting sitting with standing and walking on interstitial glucose in South Asian individuals under free-living conditions.

methodsSouth Asian adults (n = 14 [50% male]; body mass index 26.5 ± 0.8 kg·m

resultsInterstitial glucose net incremental area under the curve (iAUC) for waking hours was lower by - 9.2 mmol L

conclusionsSubstituting sitting with standing and walking under free-living conditions can be used to effectively attenuate glycaemia during waking hours, but not across 24 h, in South Asian adults. CLINICAL

trial registrationNCT04645875..

Indexed as

Blood GlucoseObesityOverweightSitting PositionStanding PositionWalkingAdultAsian PeopleFemaleHumansMaleMiddle AgedPostprandial PeriodBlood GlucoseCardiometabolic healthFlash glucose monitoringObesityPhysical activityProlonged sitting

Identifiers

PMID40764840
PMCPMC12881178

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.