Evidence map›Paper›PMID 40764834›Full record

ReviewNature reviews. Cardiology2026

Artificial intelligence-enhanced echocardiography in cardiovascular disease management.

Peder L Myhre, Bjørnar Grenne, Federico M Asch, Victoria Delgado, Rohan Khera, Stéphane Lafitte, Roberto M Lang, Patricia A Pellikka, Partho P Sengupta, Sreekanth Vemulapalli and 1 more

Abstract readReview
In one paragraph

Review in Nature reviews. Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Echocardiographic Assessment After Heart Transplant.Diagnostics (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. EchoVisuALL: From Echocardiography to Gene Discovery.bioRxiv : the preprint server for biology · 2026
    Article
  17. Article
  18. AI-Enhanced POCUS in Emergency Care.Diagnostics (Basel, Switzerland) · 2026
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peder L Myhre *K.G. Jebsen Center for Cardiac Biomarkers, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Bjørnar Grenne *Department of Circulation and Medical Imaging, NTNU: Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-2984-6865
Federico M AschMedStar Health Research Institute and Georgetown University, Washington, DC, USA.ORCID 0000-0002-1744-5271
Victoria DelgadoHeart Institute, University Hospital Germans Trias i Pujol, Badalona, Spain.ORCID 0000-0002-9841-2737
Rohan KheraSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9467-6199
Stéphane LafitteBordeaux University, Bordeaux, France.
Roberto M LangUniversity of Chicago Medical Center, Chicago, IL, USA.
Patricia A PellikkaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-6800-3521
Partho P SenguptaDivision of Cardiovascular Diseases and Hypertension, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Sreekanth VemulapalliDivision of Cardiology, Duke University School of Medicine, Durham, NC, USA.
Carolyn S P LamNational Heart Centre, Singapore and Duke-National University of Singapore, Singapore, Singapore. Carolyn.lam@duke-nus.edu.sg.ORCID 0000-0003-1903-0018

Funding

2/2 IMPRroving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)U24HL165029 · NHLBI · DUKE UNIVERSITY · PI Sean M O'Brien, Sreekanth Vemulapalli · 2023 to 2026
$2.9M
Deep learning enhanced detection and personalized monitoring of aortic stenosis - The DETECT-AS StudyR01AG089981 · NIA · YALE UNIVERSITY · PI Rohan Khera · 2024 to 2026
$2.4M
BEST-VIVA Registry (vCLI)R01HL141213 · NHLBI · DUKE UNIVERSITY · PI PATEL, MANESH R, VEMULAPALLI, SREEKANTH · 2019 to 2021
$2.3M
Translating Personalized Inference from Randomized Clinical Trials to Real-World Cardiovascular CareR01HL167858 · NHLBI · YALE UNIVERSITY · PI Rohan Khera · 2024 to 2026
$2.3M
2/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)U24HL171356 · NHLBI · DUKE UNIVERSITY · PI Shrikant I Bangdiwala, Jackie Bosch · 2024 to 2026
$2.2M
Machine Learning Guided Precision Genetic Testing for Identification of Monogenic Cardiovascular DisordersR01HL168940 · NHLBI · DUKE UNIVERSITY · PI Svati H. Shah, Sreekanth Vemulapalli · 2024 to 2026
$2.1M
Cardiac Ultrasound Radiomics-Guided Deep Neural Networks for Acute Myocardial Infarction Precision PhenotypingR01HL173998 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Partho P Sengupta · 2025 to 2026
$1.2M
Evaluating and Improving Utilization of Evidence-Based Medical Therapy in Patients with Heart Failure using Automated Tools in the Electronic Health RecordK23HL153775 · NHLBI · YALE UNIVERSITY · PI KHERA, ROHAN · 2021 to 2025
$918k
NHLBI NIH HHS K23 HL153775NHLBI NIH HHS R01 HL141213NHLBI NIH HHS R01 HL167858NHLBI NIH HHS R01 HL168940NHLBI NIH HHS R01 HL173998NHLBI NIH HHS U24 HL165029NHLBI NIH HHS U24 HL171356NIA NIH HHS R01 AG089981
6 · The paper itself

Abstract

Artificial intelligence (AI) is transforming echocardiography, ushering in an era of improved diagnostic precision, efficiency and patient care. In this Review, we present an in-depth exploration of AI applications in echocardiography, highlighting the latest advances, practical implementations and future directions. We discuss the integration of AI throughout the echocardiographic workflow, from image acquisition and analysis to interpretation. We outline the potential of AI to automate routine measurements and calculations, enable task shifting, recognize disease-specific patterns and uncover new phenogroups that might surpass current diagnostic classifications. Moreover, we address the aspects needed to create trustworthy AI systems, through careful validation, navigating regulatory requirements and upholding ethical standards, thereby presenting a balanced perspective on the advantages and limitations of this rapidly evolving technology. Through an examination of current AI applications, clinical studies and technological breakthroughs, we offer a comprehensive understanding of the evolving role of AI in the future of echocardiography and its capacity to advance cardiovascular care, while also acknowledging the current limitations of the widespread clinical implementation of AI-supported echocardiography.

Indexed as

Artificial IntelligenceCardiovascular DiseasesEchocardiographyImage Interpretation, Computer-AssistedHumansPredictive Value of Tests

Identifiers

PMID40764834
PMCPMC13628112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.