Evidence map›Paper›PMID 40764734›Full record

ArticleScientific reports2025

Prediction of hospital mortality in patients with left-sided infective endocarditis using a score in the first hours of admission.

Milena R Paixão, Bruno A M P Besen, Marilia F Felicio, Lucas Z Pocebon, Remo H M Furtado, Pedro G M de Barros E Silva, Danielle M Gualandro, Marcio S Bittencourt, Tânia M V Strabelli, Roney O Sampaio and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Milena R PaixãoDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil. milena.paixao@usp.br.ORCID http://orcid.org/0000-0002-1565-3915
Bruno A M P BesenLIM-51, Departamento de Clínica Médica, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3516-9696
Marilia F FelicioDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.
Lucas Z PocebonDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0002-6116-3765
Remo H M FurtadoDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0003-4639-1003
Pedro G M de Barros E SilvaBrazilian Clinical Research Institute, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1940-4470
Danielle M GualandroCardiology Department and Cardiovascular Research Institute Basel (CRIB) University Hospital Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0001-9041-6250
Marcio S BittencourtDepartment of Internal Medicine and Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, USA.ORCID http://orcid.org/0000-0002-3711-1754
Tânia M V StrabelliDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0003-1955-1008
Roney O SampaioDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0002-7566-2426
Flávio TarasoutchiDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0002-9964-3289
Rinaldo F SicilianoDepartment of Heart Valve Diseases, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, Bloco 2, Andar AB, São Paulo, SP, 05654-040, Brazil.ORCID http://orcid.org/0000-0002-5413-7091

Funding

Ente Cassa di Risparmio di Firenze BIANCRF181014Italian Ministry of University and Research (MUR) PRIN PNRR 20225FSFTLItalian Ministry of University and Research (MUR) RICATEN2020-2024
6 · The paper itself

Abstract

Infective endocarditis is an infection of the endocardium, associated with high morbidity and mortality, particularly when the left heart chambers are involved. Timely diagnosis and appropriate intervention can attenuate these outcomes. The objective of this study was to create and validate the EndoPredict-Px score for early in-hospital mortality prediction in patients with left-sided infective endocarditis. This analysis focused on patients admitted to the emergency department with left-sided infective endocarditis defined by the Duke-ISCVID criteria, from January 2011 to January 2020. The main outcome was in-hospital mortality. Among 530 patients with left-sided infective endocarditis, 160 (30.2%) died during hospitalization. The score included age ≥ 60 years, absence of fever, NYHA functional class III or IV heart failure, suspected embolism, hemoglobin level ≤ 10 g/dL, leukocyte level ≥ 12 × 10

Indexed as

EndocarditisHospital MortalityAdultAgedFemaleHospitalizationHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsClinical decision rulesEndocarditisHeart valve diseasesPrognostic factor

Identifiers

PMID40764734
PMCPMC12325974

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.