Evidence map›Paper›PMID 40764517›Full record

Observational studyScientific reports2025

Innovative approach to IOL-bag complex fixation with Siepser's scleral sliding knots in pseudoexfoliation syndrome.

Dario Furgiuele, Piera Giunta, Michele Rinaldi, Luca D'Andrea, Ciro Costagliola

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06423079 (Complex Intaocular Lens-Bag Fixation With Siepser's Scleral Sliding Knots), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06423079 completednot on this map

Complex Intaocular Lens-Bag Fixation With Siepser's Scleral Sliding Knots

TypeobservationalSponsorUniversity of NaplesRan2017 to 2022Enrolled36ConditionsPseudoexfoliation SyndromeArmsSiepser knots
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dario FurgiueleCasa di Cura Maria Rosaria, Pompei, Naples, Italy.
Piera GiuntaEye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.
Michele RinaldiEye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.
Luca D'AndreaEye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy. dandrea.luca91@gmail.com.ORCID http://orcid.org/0000-0002-1964-4899
Ciro CostagliolaEye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the 1-month outcomes of visual performance and positional stability of capsule-fixated intraocular lenses (IOLs) in patients with IOL-Bag complex dislocation. We enrolled 36 eyes (34 patients) with IOL-Bag complex dislocation due to pseudoexfoliation syndrome. Patients with intraoperative complications or prior posterior capsule Nd-YAG laser were excluded. Surgical intervention involved creating a superior service keratotomy and using introflective sutures for IOL fixation. Best Corrected Visual acuity (BCVA), endothelial cell counts, and tonometry were assessed at multiple postoperative time points. We also evaluated the mean spherical equivalent (SE), and the residual cylinder and sphere at each follow-up. This study has been successfully registered on ClinicalTrials.gov public (Identifier NCT06423079). The study included 36 eyes, with 22 having a one-piece IOL, 2 with a one-piece IOL plus capsular tension ring, and 12 with a three-piece IOL. Our technique demonstrates a statistically significant improvement in BCVA 1 year after surgery compared to BCVA at the time of IOL dislocation (preoperative BCVA 1.45 ± 0.81 vs 1 year 0.06 ± 0.09 logMAR; p < 0.001). There were no statistically significant differences when comparing the BCVA before the IOL dislocation with the 1-year post-operative BCVA (p > 0.13). No intraocular pressure fluctuations (preoperative IOP 15.0 ± 2.43 vs 1 year IOP 14.69 ± 2.27 p > 0.3), changes in endothelial cell counts (CC) (Preoperative CC: 1812 ± 461 cell/mm

Indexed as

Exfoliation SyndromeLenses, IntraocularLens Implantation, IntraocularScleraAgedAged, 80 and overFemaleHumansMaleMiddle AgedSuture TechniquesTreatment OutcomeVisual AcuityCapsule-fixated IOLIntraocular lens (IOL) dislocationMinimally invasive surgeryPseudoexfoliation syndromeScleral fixationSiepser knot

Identifiers

PMID40764517
PMCPMC12377345

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.