Evidence map›Paper›PMID 40764254›Full record

ArticleParasitology2025

From clinical research to public health action: addressing chronic female genital schistosomiasis in non-endemic countries.

Silvia Roure, Lorena Serrano, Xavier Vallès, Raquel Cera, Cristina Serra, Mercedes Vicente, Josep Maria Llibre, Olga Pérez-Quílez, Israel López-Muñoz, Carme Miralles and 3 more

Abstract read
In one paragraph

Article in Parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Silvia RoureInternational Health Program (PROSICS), Direcció Territorial de Malalties Infeccioses Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.ORCID https://orcid.org/0000-0002-7982-0890
Lorena SerranoSexual and Reproductive Health Care Program, Granollers branch, Barcelona North Metropolitan Primary Care Directorate, Granollers, Spain.
Xavier VallèsInternational Health Program (PROSICS), Direcció Territorial de Malalties Infeccioses Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Raquel CeraSexual and Reproductive Health Care Program, Mataró branch, Barcelona North Metropolitan Primary Care Directorate Sexual and Reproductive Health, Mataró, Spain.
Cristina SerraSexual and Reproductive Health Care Program, Granollers branch, Barcelona North Metropolitan Primary Care Directorate, Granollers, Spain.
Mercedes VicenteSexual and Reproductive Health Care Program, Granollers branch, Barcelona North Metropolitan Primary Care Directorate, Granollers, Spain.
Josep Maria LlibreFundació Lluita contra les Infeccions, Badalona, Spain.
Olga Pérez-QuílezInternational Health Program (PROSICS), Direcció Territorial de Malalties Infeccioses Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Israel López-MuñozInternational Health Program (PROSICS), Direcció Territorial de Malalties Infeccioses Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Carme MirallesCanovelles Primary Health Care Unit, Barcelona North Metropolitan Health Directorate, Institut Català de la Salut, Granollers, Spain.
Carmen CondeCanovelles Primary Health Care Unit, Barcelona North Metropolitan Health Directorate, Institut Català de la Salut, Granollers, Spain.
Laura Hernández-LeónPathology department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Ainhoa BorràsSexual and Reproductive Health Care Program, Mataró branch, Barcelona North Metropolitan Primary Care Directorate Sexual and Reproductive Health, Mataró, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analysed the early results of a screening and management protocol of imported female genital schistosomiasis (FGS) among migrant women from endemic countries. In total we screened 136 women, from which 39 had suspicion of FGS (serology-positive test and clinical signs and symptoms compatible). Median age was of 42.7 years [interquartile range (IQR 35-45)], median time living in the Europe (EU) was of 14 years (IQR 10-19) and all of them were coming from a West African country, mainly Senegal (17 out of 39; 43.6%). All of them had 1 or more clinical genitourinary findings [median 5 (IQR 2-6)], being the most prevalent pelvic pain, vaginal discharge and menstrual disorders. According to the protocol, colposcopy and cytology examination was performed in 11 participants, from whom 7 had findings compatible with FGS and 5 had low-grade cervical dysplasia with human papillomavirus (HPV)-negative results. After specific treatment with praziquantel (PZQ), we observed a high rate of resolution of clinical signs and symptoms, serology clearance at the 12th month of follow-up. Colposcopy lesions of 3 women assessed at the end of follow-up were fully resolved. Our findings and previous research support the implementation of management protocols of FGS in non-endemic countries, in spite of the knowledge gaps that still remain. Clinical trials need further assessment to determine the efficacy of PZQ, new diagnostic tools and the interaction between FGS, HPV and cervical cancer.

Indexed as

Schistosomiasis haematobiaAdultAnthelminticsChronic DiseaseEuropeFemaleHumansMiddle AgedPraziquantelPublic HealthSchistosoma haematobiumSenegalTransients and MigrantsAnthelminticsPraziquantelchronic schistosomiasisfemale genital schistosomiasismigrant populationnon-endemic countryscreening

Identifiers

PMID40764254
PMCPMC13124290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.