Evidence map›Paper›PMID 40764167›Full record

ReviewFertility and sterility2025

Fertility preservation and mental health among cancer patients of reproductive age.

Julia Stal, Catherine Benedict, Ann H Partridge, Cristina Pozo-Kaderman, Jennifer W Mack

Abstract readReview
In one paragraph

Review in Fertility and sterility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The experience of fertility preservation decision-making in hematopoietic stem cell transplantation patients: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Tumor-metabolism integrated therapy: A new paradigm for fertility-sparing treatment in endometrial cancer.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia StalDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address: julia_stal@dfci.harvard.edu.
Catherine BenedictDepartment of Psychiatry and Behavioral Science, Stanford University School of Medicine, Palo Alto, California; Stanford Cancer Institute, Stanford, California.
Ann H PartridgeDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Cristina Pozo-KadermanHarvard Medical School, Boston, Massachusetts; Department of Supportive Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts.
Jennifer W MackDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

Funding

Fertility legislation and unmet needs: Exploring intervenable barriers for quality oncofertility care among adolescent and young adult cancer patientsK00CA284291 · NCI · DANA-FARBER CANCER INST · PI Julia Stal · 2024 to 2026
$310k
NCI NIH HHS K00 CA284291
6 · The paper itself

Abstract

Many cancer patients and survivors of reproductive age report parenthood as one of their most important life goals. As a result, infertility, interruption to childbearing, or inability to conceive can have profound negative mental health impacts for this population, who often report fertility-related distress, depression, anxiety, and reproductive concerns. Most patients who preserve fertility report feeling confident in their decision, even if preservation outcomes are not favorable, whereas patients who do not preserve fertility report higher rates of decisional regret. Integrating mental health into clinical models of oncofertility care delivery is critical to ensure that patients with new, persistent, or worsening psychological symptoms are captured and appropriately cared for. We aim to underscore the importance of supportive mental health care provided in tandem with reproductive health care for reproductive-aged cancer patients and survivors before, during, and after treatment.

Indexed as

Cancer SurvivorsFertilityFertility PreservationInfertilityMental HealthNeoplasmsAdultAge FactorsFemaleHumansMalecancerFertility preservationmental healthoncofertilityreproductive concerns

Identifiers

PMID40764167
PMCPMC12360784

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.