Evidence map›Paper›PMID 40764068›Full record

ArticleBMJ open2025

Arrhythmia burden, symptoms and quality of life in female and male endurance athletes with paroxysmal atrial fibrillation: a multicentre cohort study in Norway, Australia and Belgium.

Turid Apelland, Jon Magne Letnes, Kristel Janssens, Guido Claessen, Arnljot Tveit, Andreas Berg Sellevold, Amy Mitchell, Rik Willems, Sophia Onarheim, Steve Enger and 7 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04991337 (Effects of Detraining in Endurance Athletes With Atrial Fibrillation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04991337 naunknown statusnot on this map

Effects of Detraining in Endurance Athletes With Atrial Fibrillation (NEXAF Detraining)

TypeinterventionalSponsorVestre Viken Hospital TrustRan2022 to 2024Enrolled120ConditionsAtrial FibrillationArmsDetraining group, Control group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Turid ApellandDepartment of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway turid.apelland@vestreviken.no.ORCID http://orcid.org/0000-0001-9638-7681
Jon Magne LetnesClinic of Cardiology, Trondheim University Hospital St Olav's Hospital, Trondheim, Norway.ORCID http://orcid.org/0000-0002-2877-9904
Kristel JanssensHEART Laboratory, St Vincent's Institute of Medical Research, Melbourne, Victoria, Australia.ORCID http://orcid.org/0009-0004-3176-6751
Guido ClaessenDepartment of Cardiovascular Diseases, KU Leuven, Leuven, Belgium.
Arnljot TveitInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.
Andreas Berg SellevoldClinic of Cardiology, Trondheim University Hospital St Olav's Hospital, Trondheim, Norway.
Amy MitchellHEART Laboratory, St Vincent's Institute of Medical Research, Melbourne, Victoria, Australia.
Rik WillemsCardiology, KU Leuven University Hospitals Leuven Gasthuisberg Campus, Leuven, Belgium.
Sophia OnarheimDepartment of Medical Research, Bærum sykehus, Gjettum, Norway.
Steve EngerDepartment of Medical Research, Bærum sykehus, Gjettum, Norway.
Sevda Ece KizilkilicFaculty of Medicine and Life Sciences, Biomedical Research Institute, Diepenbeek, Belgium.
Hielko MiljoenCardiology, University Hospital Antwerp, Edegem, Belgium.ORCID http://orcid.org/0000-0001-6568-451X
Adrian ElliottDiscipline of Physiology, University of Adelaide, Adelaide, South Australia, Australia.
Jan Pal LoennechenClinic of Cardiology, Trondheim University Hospital St Olav's Hospital, Trondheim, Norway.
Andre La GercheSt Vincent's Hospital Melbourne Pty Ltd, Fitzroy, Victoria, Australia.
Marius MyrstadDepartment of Medical Research, Bærum sykehus, Gjettum, Norway.ORCID http://orcid.org/0000-0002-9682-5255
NEXAF Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess atrial fibrillation (AF) burden, symptoms and quality of life (QoL) in endurance athletes with paroxysmal AF.

designProspective cohort study. SETTING AND

participantsOtherwise healthy endurance athletes with paroxysmal AF in Norway, Australia and Belgium. The current study presents baseline measurements collected before the intervention of a randomised controlled trial on effects of individually tailored training adaptation.

methodsAF burden (percentage time in AF) was measured by insertable cardiac monitors (Confirm Rx, Abbott). AF-related symptoms and QoL were assessed using the Atrial Fibrillation Effect on QualiTy-of-Life Questionnaire (AFEQT) with any score <80 defined as clinically relevant.

results43 athletes (age 57±10 (mean±SD), range 33-75 years, 3 women) were included. The athletes were monitored for 50±18 days. Median AF burden was 0.18% (IQR 0%-2.6%). Out of 29 athletes with at least one AF episode, 21 (72%) had AF episodes >60 min. 13 athletes (30%) had AFEQT overall score <80, indicating reduced QoL, and 23 athletes (53%) had significant symptoms. AF burden above median, and episodes >60 min were associated with reduced QoL (mean AFEQT score 78 vs 90, p=0.001 and 78 vs 90, p=0.001, respectively). There were large individual variations between the athletes concerning AF burden, symptoms and QoL.

conclusionsAlthough most athletes were still competing, more than half had troublesome symptoms. One-third had reduced QoL, which was associated with higher AF burden and longer duration of AF episodes. Variations between the athletes highlight the need for individually tailored AF management in athletes with paroxysmal AF. TRIAL REGISTRATION NUMBER: NCT04991337.

Indexed as

AthletesAtrial FibrillationQuality of LifeAdultAgedAustraliaBelgiumCost of IllnessFemaleHumansMaleMiddle AgedNorwayPhysical EnduranceProspective StudiesSurveys and QuestionnairesAdult cardiologyCARDIOLOGYQuality of LifeSPORTS MEDICINE

Identifiers

PMID40764068
PMCPMC12336556

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.