Evidence map›Paper›PMID 40763981›Full record

ArticleBMJ global health2025

The Immunization Agenda 2030 Strategy to reach zero-dose children in low-income and middle-income countries: a scoping review.

Audrey Beaulieu, Joelle Ducharme, Céline Thibeault, Bangaman C Akani, Daniela Ziegler, Dan Hogan, Gustavo C Corrêa, Heidi W Reynolds, Mira Johri

Abstract readScoping Review
In one paragraph

Article in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Audrey BeaulieuGavi, the Vaccine Alliance, Le Grand-Saconnex, Geneva, Switzerland.ORCID 0009-0003-7827-4351
Joelle DucharmeGavi, the Vaccine Alliance, Le Grand-Saconnex, Geneva, Switzerland.ORCID 0000-0001-5321-4406
Céline ThibeaultCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.ORCID 0009-0001-1391-6574
Bangaman C AkaniCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.ORCID 0000-0002-0031-315X
Daniela ZieglerCentre hospitalier de l'Université de Montréal, Montréal, Québec, Canada.ORCID 0000-0002-7210-5296
Dan HoganGavi, the Vaccine Alliance, Le Grand-Saconnex, Geneva, Switzerland.ORCID 0000-0003-1636-2594
Gustavo C CorrêaGavi, the Vaccine Alliance, Le Grand-Saconnex, Geneva, Switzerland.ORCID 0000-0003-2125-9364
Heidi W ReynoldsGavi, the Vaccine Alliance, Le Grand-Saconnex, Geneva, Switzerland.ORCID 0000-0003-2077-6773
Mira JohriCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada mira.johri@umontreal.ca.ORCID 0000-0001-5642-787X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntensified efforts are needed to achieve the Immunization Agenda 2030 (IA2030) target to halve the number of children not reached by routine vaccination ('zero-dose' (ZD) children) by 2030. This scoping review maps and synthesises the scientific literature on ZD children in low-income and middle-income countries since the IA2030 launch.

methodsOur protocol, developed per the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) guidelines, was registered on the Open Science Framework prior to execution, and our search strategies were designed by a research librarian. We searched MEDLINE (Ovid), CINAHL Complete (EBSCOhost), EBM Reviews (Ovid), EMBASE (Ovid), LILACS and Google Scholar for peer-reviewed studies with quantitative evidence on ZD children published between January 2020 and January 2024. Using Covidence, we screened citations in a two-stage process by two independent reviewers and conducted data charting using a pretested form. Disagreements were resolved by consensus or consultation with a senior reviewer.

resultsOf the 82 articles included, 73 provided evidence on prevalence, and/or distribution, 24 on barriers to vaccination services and 44 on deprivations faced by ZD children, their households and communities, with the risk of deprivations varying importantly across contexts. The barriers to vaccination most reported related to the intent to vaccinate (n=20), followed by community access (n=10). Deprivations mainly concerned access to health services, such as low utilisation of maternal health services (n=22), and other key development indicators, such as low socioeconomic status (n=29) and poor maternal education/literacy (n=28). We found no studies (n=0) on interventions focused on reaching ZD children with routine immunisation services.

conclusionOur findings highlight the imperative to generate evidence on interventions delivering routine immunisation to ZD children and missed communities. Results also underscore the need for transformative approaches that address multiple deprivations using carefully selected, integrated services, tailored to context-specific needs.

Indexed as

Developing CountriesImmunizationImmunization ProgramsVaccinationChildChild, PreschoolHumansInfantChild healthDelivery of Health CareImmunisationUniversal Health CareVaccines

Identifiers

PMID40763981
PMCPMC12336475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.