Fluorescence recovery in the super-resolution regime reveals subcompartments of 53BP1 foci.

Chengchen Wu, Janeth Catalina Manjarrez-González, Muntaqa Choudhury, Noor Shamkhi, Siwen Ding, Vishnu M Nair, Viji M Draviam

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In one paragraph

Article in Cell reports methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chengchen WuCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Janeth Catalina Manjarrez-GonzálezCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Muntaqa ChoudhuryCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Noor ShamkhiCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Siwen DingCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Vishnu M NairCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Viji M DraviamCentre for Cell Dynamics, Centre for Molecular Cell Biology, School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK. Electronic address: v.draviam@qmul.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Double-strand break (DSB) repair protein 53BP1 (p53 binding protein-1) mediates long-range DNA end-joining and heterochromatin maintenance. We exploit lattice structured illumination microscopy (SIM) (dual iterative SIM [diSIM, also called SIM

Indexed as

Fluorescence Recovery After PhotobleachingTumor Suppressor p53-Binding Protein 1Green Fluorescent ProteinsHumansMicroscopy, FluorescenceGreen Fluorescent ProteinsTP53BP1 protein, humanTumor Suppressor p53-Binding Protein 153BP1CP: ImagingDNA damage repair dynamicsDNA double-strand break (DSB) and long-term live-cell imagingDNA repair subcompartmentsFRAP and super-resolutionstructured illumination microscopy

Identifiers

PMID40763743

DOI10.1016/j.crmeth.2025.101118

PMCPMC12461648

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.