Evidence map›Paper›PMID 40763327›Full record

ArticleBiomacromolecules2025

Heterofunctional Cationic Polyester Dendrimers as Antibacterial Agents: The Role of Internal and External Charges.

Arunika Singh, Natalia Sanz Del Olmo, Michael Malkoch

Abstract read
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arunika SinghDepartment of Fibre and Polymer Technology, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden.ORCID 0000-0003-1683-6016
Natalia Sanz Del OlmoDepartment of Fibre and Polymer Technology, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden.ORCID 0000-0001-9946-8073
Michael MalkochDepartment of Fibre and Polymer Technology, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden.ORCID 0000-0002-9200-8004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is a global health crisis, necessitating novel antibacterial strategies. Polycations, particularly polyester dendrimers, are promising due to their structural precision and membrane-disruptive mechanisms. However, existing dendrimers lack versatility in charge distribution, limiting their antibacterial efficacy. Here, we report two families of cationic polyester dendrimers (up to the third generation) with either internal or combined internal and external charges compared with traditional bis-MPA dendrimers bearing only external cations. These heterofunctional dendrimers, built from AB

Indexed as

Anti-Bacterial AgentsDendrimersPolyestersCationsEscherichia coliHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsCationsDendrimersPolyesters

Identifiers

PMID40763327
PMCPMC12421690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.