Evidence map›Paper›PMID 40763131›Full record

Trial reportPloS one2025

Acceptability and implementation potential of a health literacy intervention to increase colorectal cancer screening in deprived areas: A qualitative study of patients and general practitioners participating in a cluster randomized controlled trial.

Alix Boirot, Maria Claudia Addamiano, Clémence Casanova, Niamh M Redmond, Géraldine Cazorla, Michel Rotily, Anne-Marie Schott-Petelaz, Christian Balamou, Zineb Doukhi, Myriam Kaou and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alix BoirotAix Marseille Univ, Inserm, IRD, ISSPAM, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.ORCID https://orcid.org/0009-0008-8888-4440
Maria Claudia AddamianoEQUITY research team (Certified by the French League Against Cancer), CERPOP, UMR, Inserm, Université Toulouse III Paul Sabatier, France.
Clémence CasanovaAix Marseille Univ, Inserm, IRD, ISSPAM, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.
Niamh M RedmondEQUITY research team (Certified by the French League Against Cancer), CERPOP, UMR, Inserm, Université Toulouse III Paul Sabatier, France.ORCID https://orcid.org/0000-0001-8814-3396
Géraldine CazorlaAix Marseille Univ, Inserm, IRD, ISSPAM, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.ORCID https://orcid.org/0009-0008-8904-4195
Michel RotilyCentre d'Etudes et de Recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université, Marseille, France.ORCID https://orcid.org/0009-0008-7332-7799
Anne-Marie Schott-PetelazResearch on Healthcare Performance (RESHAPE) INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
Christian BalamouCentre Régional de Coordination du Dépistage des Cancers en Auvergne-Rhône-Alpes - CRCDC-AuRA, Site de l'Ain, Bourg-en-Bresse, France.
Zineb DoukhiDMU PRISME Délégation à la Recherche Clinique et à l'innovation (DRCI), Unité d'épidémiologie Clinique/ CIC-EC 1426 - INSERM, France.
Myriam KaouResearch on Healthcare Performance (RESHAPE) INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
Françoise CouranjouAssistance Publique des Hôpitaux de Marseille (APHM), Direction de la Recherche en santé, Marseille, France.
Julien ManciniAix Marseille Univ, Inserm, IRD, ISSPAM, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.
Cyrille DelpierreEQUITY research team (Certified by the French League Against Cancer), CERPOP, UMR, Inserm, Université Toulouse III Paul Sabatier, France.
Marie-Anne DurandThe Dartmouth Institute for Health Policy & Clinical Practice, Dartmouth College, Lebanon, New Hampshire, United States of America.
Aurore LamourouxAPHM, Centre de Santé Universitaire - Espace Santé Aygalades, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer (CCR) is one of the leading causes of death worldwide. Early detection remains a highly effective strategy for curing this disease. In France, despite a free organised screening programme for people aged between 50 and 74, participation rates remain suboptimal. Socioeconomic position and health literacy levels exacerbate the situation, with the lowest screening rates observed in the most socially disadvantaged areas. This study assessed patients' and General Practitioners' (GP) views on the acceptability of an intervention to increase screening uptake using a simple brochure and video on the importance and process of CCR screening.

methodWe conducted a cross-sectional qualitative study using semi-structured interviews with patients (n = 24) and GPs (n = 22) who used or participated in the DECODE project intervention. The interviews were conducted by telephone or videoconference and analysed thematically using Nvivo software and dual independent coding.

results95% of GPs expressed a clear preference for the video over the brochure. Patients had varied results with 50% preferring the video, as it demonstrated how to do the test, versus the brochure. The humorous and de-dramatising aspects of the video were the two key factors highlighted by interviewees. However, support from healthcare staff (GPs, nurses, etc.) is still essential, in supporting patients in prevention. This presents a challenge for GPs, who are frequently constrained by time limitations during consultations.

conclusionOur findings emphasize the need to tailor promotional materials for both patients and healthcare professionals to improve CCR screening uptake, balancing digital efficiency with maintaining core human relationships in healthcare. Such intervention can be integrated into different workflows. The addition of video into national CRC screening programs might also help. Targeting CRC screening interventions at provider-patient interactions, ensuring they are tailored, accessible, and engaging, is key to reducing disparities.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerGeneral PractitionersHealth LiteracyPatient Acceptance of Health CareAdultAgedCross-Sectional StudiesFemaleFranceHumansMaleMass ScreeningMiddle AgedQualitative Research

Identifiers

PMID40763131
PMCPMC12324091

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.