Evidence map›Paper›PMID 40763064›Full record

ArticleJournal of neurophysiology2025

Role of voltage-gated Ca

Hannah J Goudsward, Victor Ruiz-Velasco, Salvatore L Stella, Gregory M Holmes

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah J GoudswardDepartment of Neuroscience and Experimental Therapeutics, Penn State University College of Medicine, Hershey, Pennsylvania, United States.
Victor Ruiz-VelascoDepartment of Anesthesiology and Perioperative Medicine, Penn State University College of Medicine, Hershey, Pennsylvania, United States.ORCID 0000-0003-3614-5028
Salvatore L StellaDepartment of Neuroscience and Experimental Therapeutics, Penn State University College of Medicine, Hershey, Pennsylvania, United States.
Gregory M HolmesDepartment of Neuroscience and Experimental Therapeutics, Penn State University College of Medicine, Hershey, Pennsylvania, United States.ORCID 0000-0001-5176-8376

Funding

Pathophysiological remodeling of the enteric neuromuscular compartment in experimental spinal cord injuryR01NS105987 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HOLMES, GREGORY M. · 2019 to 2023
$1.7M
Ghrelin Modulation of CaV 2.2 Channels After Spinal Cord InjuryF31DK136279 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GOUDSWARD, HANNAH J · 2023 to 2024
$70k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) F31-DK-136279HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01-NS-105987NIDDK NIH HHS F31 DK136279NINDS NIH HHS R01 NS105987PSU | Penn State College of Medicine (PSCOM) N/A
6 · The paper itself

Abstract

Upper gastrointestinal dysfunction is one of the most common comorbidities of spinal cord injury (SCI) and significantly impairs overall health and quality of life. Despite the need for targeted treatment options, the causal mechanisms underlying upper gastrointestinal dysfunction after injury remains unknown. Previous studies have demonstrated gastric vagal afferents are less sensitive to stimuli after SCI, which may be due to changes in voltage-gated Ca

Indexed as

Calcium Channels, N-TypeNeurons, AfferentNodose GanglionSpinal Cord InjuriesStomachVagus NerveAnimalsFemaleMaleRatsRats, Sprague-DawleyCalcium Channels, N-Typegastric reflexesnodose ganglionspinal cord injuryvisceral afferent signalingvoltage-gated Ca2+

Identifiers

PMID40763064
PMCPMC12416546

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.