Evidence map›Paper›PMID 40763032›Full record

ArticleThe Journal of frailty & aging2025

Associations between sarcopenia operationalized using muscle strength or power and health-related parameters.

Hélio José Coelho Júnior, Alejandro Álvarez-Bustos, Riccardo Calvani, Stefano Cacciatore, Anna Picca, Matteo Tosato, Francesco Landi, Emanuele Marzetti, Lookup Study Group

Abstract read
In one paragraph

Article in The Journal of frailty & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hélio José Coelho JúniorFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy; Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain. Electronic address: coelhojunior@hotmail.com.br.
Alejandro Álvarez-BustosBiomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain; Instituto de Investigación IdiPaz, Madrid, Spain.
Riccardo CalvaniFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Stefano CacciatoreFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Anna PiccaFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Medicine and Surgery, LUM University, Casamassima, Italy.
Matteo TosatoFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Francesco LandiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Emanuele MarzettiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: emanuele.marzetti@policlinicogemelli.it.
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Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe present study examined the associations between sarcopenia, operationalized through muscle strength or muscle power, and health parameters in Italian community-dwelling older adults.

designCross-sectional study.

settingUnconventional settings across Italy.

participantsItalian older adults (65+ years) who provided a written informed consent. MEASUREMENTS: Physical function was evaluated according to isometric handgrip strength (IHG) and 5-time sit-to-stand (5STS) performances. Muscle power parameters were estimated based on 5STS values. Sarcopenia was operationalized according to the presence of low physical function (i.e., IHG or 5STS), or low muscle power, plus low appendicular skeletal muscle mass. Health parameters included the capacity to perform the 400 m test, adherence to the Mediterranean (MED) diet, practice of physical activity (PA), blood pressure (BP) values, blood concentration of total cholesterol and glucose, verbal fluency, sleep quality, and self-reported health status.

resultsResults indicated that sarcopenic indexes had a poor-to-moderate level of agreement. Moreover, results indicated that operationalizing sarcopenia using muscle power measures provided exclusive or stronger associations with health parameters. Specifically, older adults classified as sarcopenic based on muscle power values were less likely to complete the 400-meter walk test, more likely to engage in PA, reported poorer self-rated health, and showed lower adherence to the MED diet.

conclusionsFindings of the present study indicated that sarcopenia indexes based on muscle strength or muscle power capture different aspects of older adults' health. Specifically, operationalizing sarcopenia using muscle power measures provided exclusive or stronger associations with health parameters.

Indexed as

Health StatusMuscle StrengthSarcopeniaAgedAged, 80 and overCross-Sectional StudiesDiet, MediterraneanExerciseFemaleGeriatric AssessmentHand StrengthHumansIndependent LivingItalyMaleMuscle, SkeletalDisabilityFrailtyIntrinsic capacityMediterranean dietMobilityPhysical performance

Identifiers

PMID40763032
PMCPMC12374430

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.