Evidence map›Paper›PMID 40763013›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Detecting chirality-induced spin selectivity in chromophore-linked DNA hairpins using photogenerated radical pairs.

Elisabeth I Latawiec, Alessandro Chiesa, Yunfan Qiu, Nikolai A Tcyrulnikov, Ryan M Young, Stefano Carretta, Matthew D Krzyaniak, Michael R Wasielewski

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Probing the connection between chirality and spin through time-resolved EPR spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Elisabeth I LatawiecDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0009-0002-1738-316X
Alessandro ChiesaDipartimento di Scienze Matematiche, Fisiche e Informatiche, Università di Parma, Parma I-43124, Italy.ORCID 0000-0003-2955-3998
Yunfan QiuDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0000-0002-4666-1424
Nikolai A TcyrulnikovDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0000-0001-8263-1065
Ryan M YoungDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0000-0002-5108-0261
Stefano CarrettaDipartimento di Scienze Matematiche, Fisiche e Informatiche, Università di Parma, Parma I-43124, Italy.ORCID 0000-0002-2536-1326
Matthew D KrzyaniakDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0000-0002-8761-7323
Michael R WasielewskiDepartment of Chemistry, Institute for Quantum Information Research and Engineering, and Center for Molecular Quantum Transduction, Northwestern University, Evanston, IL 60208-3113.ORCID 0000-0003-2920-5440

Funding

EC | ERC | HORIZON EUROPE European Research Council (ERC) 101071533NSF (NSF) ECCS-1542205
6 · The paper itself

Abstract

Chirality-induced spin selectivity (CISS) results in spin polarization of electrons transmitted through chiral molecules and materials. Since CISS results in spin polarization even at room temperature, it affords the possibility of using it to develop quantum technologies that can operate under ambient conditions. We have shown previously that photo-driven hole transfer within DNA hairpins provides a facile route to generate spin-correlated radical pairs (SCRPs). To study the effect of CISS on the spin dynamics of SCRPs in DNA hairpins, we prepared a series of electron donor-chiral bridge-acceptor molecules where the chiral bridge is a B-form DNA helix consisting of 4 to 6 base pairs. Naphthalene-1,8:4,5-bis(dicarboximide) (NDI) serves as the hairpin linker chromophore and electron acceptor. Photoexcitation of NDI results in rapid hole transfer through the π-stacked purine bases of the DNA and trapping of the hole on a terminal stilbene diether (Sd) to generate the NDI

Indexed as

DNABase PairingElectronsElectron Spin Resonance SpectroscopyFree RadicalsNaphthalenesNucleic Acid ConformationPhotochemical ProcessesStereoisomerismDNAFree RadicalsNaphthaleneschiralityCISSelectron transferradical ion pairspin dynamics

Identifiers

PMID40763013
PMCPMC12358874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.