Evidence map›Paper›PMID 40762962›Full record

ArticleBiomacromolecules2025

Modification of Bacterial Nanocellulose Using Nonthermal Plasma-Assisted Enzymatic Hydrolysis.

Mirva Sarafidou, Aleksander Forys, Marcin Godzierz, Anastasiia Kobyliukh, Barbara Trzebicka, Stergios Pispas, Apostolis Koutinas, Erminta Tsouko

Abstract read
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mirva SarafidouDepartment of Food Science and Human Nutrition, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece.
Aleksander ForysCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, Zabrze 41-819, Poland.ORCID 0000-0002-6994-868X
Marcin GodzierzCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, Zabrze 41-819, Poland.ORCID 0000-0001-9351-7452
Anastasiia KobyliukhCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, Zabrze 41-819, Poland.
Barbara TrzebickaCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, Zabrze 41-819, Poland.
Stergios PispasTheoretical and Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Ave., Athens 11635, Greece.ORCID 0000-0002-5347-7430
Apostolis KoutinasDepartment of Food Science and Human Nutrition, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece.ORCID 0000-0001-5245-3157
Erminta TsoukoDivision of Genetics & Biotechnology, Department of Biology, National and Kapodistrian University of Athens, Zografou Campus, Athens 15784, Greece.ORCID 0000-0002-8700-5503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the structural modification of bacterial cellulose (BC) through enzymatic hydrolysis using varying cellulase activities and substrate concentrations. Optimal hydrolysis conditions (50 U/g of BC; 20 g/L of BC) were established to balance recovery and homogeneity (yielding BNC1). Hydrolysis was further combined with nonthermal plasma by suspending BC into plasma-activated water (PAW) prior to hydrolysis (BNC2). In another approach, BC suspensions were pretreated using a plasma bubble reactor followed by hydrolysis (BNC3). BNC1 and BNC2 yields were similar (∼50%), suggesting that PAW regulated the pH during hydrolysis. BNC3 yield was significantly higher (78%) compared to BNC1, indicating that the generated radicals promoted chain modifications while minimizing glucose/cellobiose release. That dual approach led to BC defibrillation, as revealed by AFM/cryo-TEM. The reduction in melting temperature observed was correlated with a crystallinity drop. Dual enzymatic and plasma-assisted strategies offer novel-intriguing avenues to fine-tune the properties of cellulose nanocomposites for sustainable applications.

Indexed as

CellulaseCelluloseNanocompositesPlasma GasesHydrolysisCellulaseCellulosePlasma Gases

Identifiers

PMID40762962
PMCPMC12421519

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.