Evidence map›Paper›PMID 40762835›Full record

ArticleThe Journal of clinical investigation2025

Early CD4+ T cell proliferation and chronic T cell engagement impact myeloma outcomes following T cell engager therapy.

Alyssa M Duffy, Anshika Goenka, Maryam I Azeem, Azmain Taz, Sayalee V Potdar, Sara A Scott, Ellen Marin, Jonathan L Kaufman, Craig C Hofmeister, Nisha S Joseph and 5 more

Abstract read
In one paragraph

Article in The Journal of clinical investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alyssa M DuffyDepartment of Hematology/Medical Oncology.
Anshika GoenkaDepartment of Hematology/Medical Oncology.
Maryam I AzeemDepartment of Hematology/Medical Oncology.
Azmain TazDepartment of Hematology/Medical Oncology.
Sayalee V PotdarDepartment of Hematology/Medical Oncology.
Sara A ScottEmory Healthcare, and.
Ellen MarinEmory Healthcare, and.
Jonathan L KaufmanDepartment of Hematology/Medical Oncology.
Craig C HofmeisterDepartment of Hematology/Medical Oncology.
Nisha S JosephDepartment of Hematology/Medical Oncology.
Vikas A GuptaDepartment of Hematology/Medical Oncology.
Sagar LonialDepartment of Hematology/Medical Oncology.
Ajay K NookaDepartment of Hematology/Medical Oncology.
Madhav V DhodapkarTranslational Science and Therapeutics Division, Fred Hutch Cancer Center, Seattle, Washington, USA.
Kavita M DhodapkarTranslational Science and Therapeutics Division, Fred Hutch Cancer Center, Seattle, Washington, USA.

Funding

Improving immune modulation for smoldering myelomaR01CA289978 · NCI · FRED HUTCHINSON CANCER CENTER · PI MADHAV V DHODAPKAR · 2025 to 2026
$1.4M
NCI NIH HHS R01 CA289978
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CancerImmunologyImmunotherapyOncologyT cells

Identifiers

PMID40762835
PMCPMC12483553

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.