Evidence map›Paper›PMID 40762809›Full record

Trial reportPsychopharmacology2026

Methylphenidate (Ritalin) does not improve exam performance in an experimental setting.

Anke Sambeth, Monika Toth, Arjan Blokland

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anke SambethDepartment Teaching and Innovation of Learning, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, Maastricht, 6200 MD, The Netherlands. anke.sambeth@maastrichtuniversity.nl.ORCID http://orcid.org/0000-0002-3654-9383
Monika TothDepartment of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Arjan BloklandDepartment of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleSurveys indicate that about 10-20% of students use medicinal drugs to improve their exam performance. Whether these drugs really improve exam performance has not been examined in an experimental setting yet. This study tested the effects of methylphenidate (MPH; 20 mg) on exam performance either by giving the drug before studying for an exam (day 1, acquiring new information) or before the exam was taken (day 2, retrieving the information).

methodFor this study, a double-blind placebo controlled between-subjects design was applied. The participants were randomly assigned to three groups that were given treatment on the two days: Placebo-Placebo (n = 25), MPH (n = 24), Placebo-MPH (n = 26). The exam contained multiple-choice questions (factual knowledge and inference questions) and open questions (inference).

resultsThe data showed that MPH did not improve the exam performance on the three types of questions. In addition, the average grade did not differ between the three groups and the number of participants failing or passing the exam did not differ.

conclusionThis is a first experimental study showing that MPH does not improve exam performance and should discourage students to take MPH during exam periods.

Indexed as

Academic PerformanceCentral Nervous System StimulantsEducational MeasurementMethylphenidateAdolescentAdultDouble-Blind MethodFemaleHumansMaleStudentsYoung AdultCentral Nervous System StimulantsMethylphenidateExam performanceMemoryMethylphenidateRitalinStudent performance

Identifiers

PMID40762809
PMCPMC12979259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.