ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026
Antibacterial and physicochemical properties of a zinc oxide nanoparticle-modified orthodontic adhesive : An in vitro study.
Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Evaluating antibacterial efficiency of orthodontic brackets coated with copper oxide, titanium dioxide and silver nanoparticles.Bioinformation · 2026Article
- Current Developments in Antibacterial Nanoparticle-Based Dental Composite Materials: A Comprehensive Overview.International journal of dentistry · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWhite spot lesions (WSLs) can result from bacterial plaque around orthodontic brackets, leading to enamel demineralization. While other preventive strategies rely on patient compliance, incorporating zinc oxide (ZnO) nanoparticles into adhesives offers antimicrobial protection, independent of compliance. This study aimed to develop a ZnO-containing adhesive and evaluated its antibacterial and mechanical properties for clinical application.
methodsThis in vitro study, conducted at Shahid Beheshti University of Medical Sciences, sampled 30 extracted premolar teeth and randomly assigned them to three groups: (1) control (synthesized adhesive without ZnO), (2) ZnO (1.5% ZnO nanoparticles), and (3) XT (Transbond XT, 3M, St. Paul, MN, USA). The adhesive's antibacterial effect was assessed using Streptococcus mutans biofilm inhibition, while mechanical and physicochemical properties were evaluated by measuring shear bond strength (SBS), adhesive remnant index (ARI), degree of conversion (DC), water sorption, water solubility, and microhardness. Data were analyzed using one-way analysis of variance (ANOVA), Tukey's honestly significant difference (HSD), Kruskal-Wallis test, and Mann-Whitney test using SPSS software (IBM, Armonk, NY, USA). P-values less than 0.05 were considered statistically significant.
resultsStatistically significant differences were found among the three groups with respect to SBS (P = 0.023), microhardness (P < 0.001), antibacterial activity (P < 0.001), water sorption (P = 0.003), and water solubility (P < 0.001). No significant differences were observed in DC or ARI. Post hoc tests showed that ZnO outperformed the control in all properties except SBS and did not differ significantly from XT in tested properties.
conclusionIncorporating 1.5% ZnO nanoparticles into the synthesized adhesive enhanced antibacterial properties and inhibited biofilm formation without compromising bond strength, DC, water sorption, water solubility, or microhardness. Given its superior antibacterial efficacy over Transbond XT, the ZnO adhesive shows potential as a viable option for orthodontic bonding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.