Evidence map›Paper›PMID 40762700›Full record

ArticleEuropean child & adolescent psychiatry2026

Social context is a cue for tic reduction in clinical settings.

Brianna C M Wellen, Grace Bacon, David Schneck, Emily Wilton, Alison Pryor, IaOom Khang, Kelvin Lim, Kevin J Black, Erjia Cui, Mark B Fiecas and 1 more

Abstract read
In one paragraph

Article in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brianna C M WellenDepartment of Psychiatry, University of Minnesota Medical School, 2025 E River Parkway, Minneapolis, MN, 55414, USA. bwellen@umn.edu.
Grace BaconCarleton College, Psychology, Northfield, MN, USA.
David SchneckUniversity of Minnesota, Masonic Institute for the Developing Brain, Minneapolis, MN, USA.
Emily WiltonDepartment of Psychiatry, University of Minnesota Medical School, 2025 E River Parkway, Minneapolis, MN, 55414, USA.
Alison PryorNortheast Ohio Medical University, Rootstown, OH, USA.
IaOom KhangDepartment of Psychiatry, University of Minnesota Medical School, 2025 E River Parkway, Minneapolis, MN, 55414, USA.
Kelvin LimDepartment of Psychiatry, University of Minnesota Medical School, 2025 E River Parkway, Minneapolis, MN, 55414, USA.
Kevin J BlackDepartments of Psychiatry, Neurology, Radiology and Neuroscience, Washington University in St. Louis, St. Louis, MO, USA.
Erjia CuiSchool of Public Health, Division of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, MN, USA.
Mark B FiecasSchool of Public Health, Division of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, MN, USA.
Christine A ConeleaDepartment of Psychiatry, University of Minnesota Medical School, 2025 E River Parkway, Minneapolis, MN, 55414, USA.

Funding

Brain Health Across the Metabolic Continuum in Youth at Risk for T2DR01DK126826 · NIDDK · WASHINGTON UNIVERSITY · PI ARSLANIAN, SILVA A, HERSHEY, TAMARA G · 2021 to 2025
$3.2M
Longitudinal Study of Brain Imaging and Cognitive Markers of Tourette Syndrome in ChildrenR01MH118217 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2019 to 2025
$3.2M
Comorbidity: Substance Use Disorders and Other Psychiatric ConditionsT32DA037183 · NIDA · UNIVERSITY OF MINNESOTA · PI Anna Zilverstand · 2014 to 2026
$3.2M
Tourette Syndrome genetics and neuroimaging international collaborative studyR01MH126213 · NIMH · PURDUE UNIVERSITY · PI Peristera Paschou · 2022 to 2026
$2.5M
Quantification of Tics in Tourette SyndromeR01NS131314 · NINDS · UNIVERSITY OF MINNESOTA · PI Christine A Conelea · 2023 to 2026
$2.3M
Transcranial Magnetic Stimulation to Augment Behavior Therapy for TicsR61MH123754 · NIMH · UNIVERSITY OF MINNESOTA · PI CONELEA, CHRISTINE A · 2020 to 2020
$1.2M
Fractality as a quantitative assessment tool for tic disorders and functional tic-like behaviorsR21NS133875 · NINDS · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2023 to 2023
$428k
NIDA NIH HHS T32 DA037183NIDDK NIH HHS R01 DK126826NIH HHS T32DA037183NIMH NIH HHS R01 MH118217NIMH NIH HHS R01 MH126213NIMH NIH HHS R61 MH123754NIMH NIH HHS R61MH123754NINDS NIH HHS R01 NS131314NINDS NIH HHS R01NS131314NINDS NIH HHS R21 NS133875
6 · The paper itself

Abstract

Assessment and diagnosis of Tourette Syndrome and other tic disorders relies on clinical observation and self-reported history. However, tics are highly susceptible to contextual influences, including clinical interactions. We used video-based observation to quantify the contextual impact of clinician presence on tics and evaluate the potential for these methods to improve tic detection. Youth ages 12-21 (N = 39) participated in a clinical trial with video-recorded pre- and post-treatment assessments. Established methods for precision video-based behavioral coding were used to quantify tic frequency and type across assessment contexts (clinician presence and instruction to suppress tics). Participants had significantly more tics when alone and ticcing naturally (mean tics per minute [tpm] = 25.03) and when alone with suppression instructions (mean tpm = 9.48) than in the clinician's presence (mean tpm = 3.29), all ps <.001. Further, mixed model results showed a significant decrease in tpm across treatment when alone ((β = -21.85; 95% CI: [-33.99, -9.70]), and with a clinician (β = -20.31; 95% CI: [-35.08, -5.55]), but significantly greater decrease in the alone context (β = -6.01; 95% CI: [-9.74, -2.29]). Tics occurred less frequently in clinician presence than alone (even when specifically asked to suppress tics alone), suggesting that the social context of clinician presence may facilitate tic suppression that is automatic and/or learned. Additionally, results establish objective video-based measurement as a valuable tool to detect tics and tic change not visible to the clinician.

Indexed as

Behavior TherapyCuesSocial EnvironmentTic DisordersTicsTourette SyndromeAdolescentChildFemaleHumansMaleVideo RecordingYoung AdultBehavior TherapySymptom AssessmentTicsTourette Syndrome

Identifiers

PMID40762700
PMCPMC12817957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.