Evidence map›Paper›PMID 40762463›Full record

ArticleMicrobiology spectrum2025

Metabolites derived from bacterial isolates of the human skin microbiome inhibit

Viet Hoang Le, Tetyana King, Breanna Wuerzberger, Olivia R Bauer, Megan N Carver, Tiffany S Chan, Annabeth L Henson, Grace K Hubbard, Tamar Kopadze, Claire F Patterson and 6 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. MicrobioME: a CURE model for diverse microbiology laboratory classrooms.Journal of microbiology & biology education · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Viet Hoang LeDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Tetyana KingDepartment of Biology and Biotechnology, University of Houston-Clear Lake, Houston, Texas, USA.
Breanna WuerzbergerDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Olivia R BauerDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Megan N CarverDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Tiffany S ChanDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Annabeth L HensonDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Grace K HubbardDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Tamar KopadzeDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Claire F PattersonDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Sabrina M McGrawDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Aidan O'HaraDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Eryk J YarkoskyDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.
Michael G LaMontagneDepartment of Biology and Biotechnology, University of Houston-Clear Lake, Houston, Texas, USA.
Eileen M HotzeDepartment of Undergraduate Biology, The University of Kansas, Lawrence, Kansas, USA.
Rosana B R FerreiraDepartment of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, USA.ORCID 0000-0002-7162-0026

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
Kansas IDeA Network of Biomedical Research Excellence P20GM103418National Science Foundation 2320765NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM113117NIGMS NIH HHS P20GM113117
6 · The paper itself

Abstract

The human skin microbiome is a diverse ecosystem that can help prevent infections by producing biomolecules and peptides that inhibit growth and virulence of bacterial pathogens. IMPORTANCE: The skin is constantly exposed to the environment and consequently to numerous pathogens. The bacterial community that colonizes healthy skin is thought to play an important role in protecting us against infections.

Indexed as

Anti-Bacterial AgentsBiofilmsMicrobiotaSkinStaphylococcus aureusBacillusHumansSkin MicrobiomeSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStaphylococcus epidermidisAnti-Bacterial Agentsanti-biofilm activityBacillusbiofilmsMALDI-TOFskin microbiotaStaphylococcus

Identifiers

PMID40762463
PMCPMC12403628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.