Evidence map›Paper›PMID 40762245›Full record

ArticleRapid communications in mass spectrometry : RCM2025

Isotopologue Ratios Identify

Janina Groninga, Julius Lipp, Min Song, Kai-Uwe Hinrichs

Abstract read
In one paragraph

Article in Rapid communications in mass spectrometry : RCM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Isotopologue Ratios IdentifyRapid communications in mass spectrometry : RCM · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janina GroningaMARUM - Center for Marine Environmental Sciences, and Faculty of Geosciences, University of Bremen, Bremen, Germany.ORCID https://orcid.org/0009-0007-4577-3532
Julius LippMARUM - Center for Marine Environmental Sciences, and Faculty of Geosciences, University of Bremen, Bremen, Germany.
Min SongMARUM - Center for Marine Environmental Sciences, and Faculty of Geosciences, University of Bremen, Bremen, Germany.ORCID https://orcid.org/0000-0002-3291-0282
Kai-Uwe HinrichsMARUM - Center for Marine Environmental Sciences, and Faculty of Geosciences, University of Bremen, Bremen, Germany.

Funding

Deutsche Forschungsgemeinschaft EXC-2077-390741603
6 · The paper itself

Abstract

rationaleThe stable carbon isotopic composition (δ

methodsWe performed ultra-high-performance liquid chromatography/electrospray ionization/high-resolution mass spectrometry (UHPLC/ESI/HRMS) to analyze standards of archaeol and lipid extracts from a diverse set of sediment samples of a hydrothermal methane seep system. Using the ratio of the M1 isotopologue over the monoisotopic isotopologue M0, we calculated the δ

resultsδ

conclusionsOur results highlight that the M1/M0 ratio from UHPLC/HRMS measurements can be utilized to evaluate the carbon isotopic fingerprint of non-GC-amenable lipids and to reliably detect lipid biomarkers putatively associated with microbial methane turnover carrying extremely depleted isotopic signatures. This paves the way for a comprehensive exploration of intact lipids associated with microbial methane turnover in environmental samples.

Indexed as

Carbon IsotopesGeologic SedimentsLipidsMethaneBiomarkersChromatography, High Pressure LiquidGas Chromatography-Mass SpectrometryGlyceryl EthersSpectrometry, Mass, Electrospray Ionizationarchaeol lipidBiomarkersCarbon-13Carbon IsotopesGlyceryl EthersLipidsMethanecompound‐specific isotope analysis (CSIA)high‐resolution‐MSmethane turnovermicrobial lipidsstable carbon isotopesUHPLC/MS

Identifiers

PMID40762245
PMCPMC12322946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.