Evidence map›Paper›PMID 40762118›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Chiral Induction and Memory via Supramolecular Deracemization.

Robert Hein, Eric Sidler, Yohan Gisbert, Ben L Feringa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Chiral Induction and Memory via Supramolecular Deracemization.Angewandte Chemie (International ed. in English) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert Hein *Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 3, Groningen, 9747 AG, The Netherlands.ORCID https://orcid.org/0000-0001-8567-0924
Eric Sidler *Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 3, Groningen, 9747 AG, The Netherlands.
Yohan GisbertStratingh Institute for Chemistry, University of Groningen, Nijenborgh 3, Groningen, 9747 AG, The Netherlands.
Ben L FeringaStratingh Institute for Chemistry, University of Groningen, Nijenborgh 3, Groningen, 9747 AG, The Netherlands.ORCID https://orcid.org/0000-0003-0588-8435

Funding

Bonus Incentive Scheme and Gravitation Program 024.001.035Dutch Ministry of Education, Culture and ScienceLiebig FellowshipMarie Skłodowska-Curie Postdoctoral Fellowship 101060079Marie Skłodowska-Curie Postdoctoral Fellowship 101063933Return Fellowship by the state of North Rhine-WestphaliaSwiss National Science Foundation P500PN_214313
6 · The paper itself

Abstract

Chirality is intrinsic to nature, and control of molecular chirality remains at the forefront of the chemical sciences. The introduction of fundamentally new principles to break symmetry, leading to the formation of a specific enantiomer, is particularly challenging with important implications in numerous scientific fields. Herein we present a helically chiral dynamic molecular switch whose enantiomers are connected via a single symmetric metastable state that can be populated via light or redox stimuli. Relaxation of the prochiral state in the presence of a bound chiral ammonium guest results in the preferential formation of a specific enantiomer through a conceptually unique supramolecular deracemization process. Importantly, the formed host enantiomer is stable even in the absence of guest, enabling reversible and stable chiral information transfer, while oxidation of the host results in an enantioenriched dication that is insensitive to light, allowing orthogonal chiral memory.

Indexed as

Chiral inductionChiral memoryDeracemizationHost‐guest systemsMolecular switchOvercrowded alkene

Identifiers

PMID40762118
PMCPMC12435425

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.