Evidence map›Paper›PMID 40761931›Full record

ArticleFrontiers in public health2025

Identification and trajectory of multimorbidity patterns among older people in China: a longitudinal study based on the China health and retirement longitudinal study 2011-2020 data.

Qian Liu, Shuzhi Lin, Lin Yin, Wei Liu, Xiaoying Zhu, Zimeng Li, Yifang Shen, Bianling Feng

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian LiuThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Shuzhi LinThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Lin YinThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Wei LiuThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Xiaoying ZhuThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Zimeng LiThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Yifang ShenThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Bianling FengThe Department of Pharmacy Administration, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multimorbidity presents a significant global health challenge, particularly among older people in China; however, research on its patterns and dynamic evolution remains limited. This study examines chronic disease co-occurrence and associated risk factors, identifying multimorbidity trends to inform health management and policy. Methods: This study utilized the latest five-wave national survey data from the China Health and Retirement Longitudinal Study (CHARLS) on 2,798 individuals aged 60 years or older with multimorbidity. Latent class analysis (LCA) identified distinct multimorbidity patterns from 14 self-reported chronic conditions. Longitudinal follow-up data were then used to construct transition frequency matrices, modeling the trajectory and dynamic evolution of multimorbidity among older people in China over time. Results: Using LCA, 2,798 participants were classified into four patterns: the multi-system disorder group (10.33%), the gastrointestinal metabolism group (44.07%), the cardiovascular disease group (37.81%), and the respiratory disease group (7.79%). Over five waves, the gastrointestinal metabolism group declined (from 74.70% in 2011 to 44.07% in 2020), while the cardiovascular group increased (from 15.87 to 37.81%). The multi-system and respiratory groups also grew. Transition analysis showed the gastrointestinal metabolism group was the least stable, with many shifting to the cardiovascular group (7.29% from 2013 to 2015, 23.81% from 2015 to 2018, 18.54% from 2018 to 2020). Conclusion: The disease burden among older people is shifting from gastrointestinal metabolism disorders to cardiovascular diseases, with gastrointestinal issues potentially acting as precursors to cardiovascular conditions. Future research should investigate the risk factors influencing transitions between multimorbidity patterns and their underlying mechanisms.

Indexed as

MultimorbidityAgedAged, 80 and overCardiovascular DiseasesChinaChronic DiseaseFemaleHumansLatent Class AnalysisLongitudinal StudiesMaleMiddle AgedRetirementRisk FactorsChinadisease trajectorymultimorbidityolder populationspublic health

Identifiers

PMID40761931
PMCPMC12318766

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.