ArticleFrontiers in medicine2025
Interocular differences in choroidal thickness and circulation in anisomyopic adults and their association with myopia severity.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A natural experiment in school lighting: observational evidence linking far-red light exposure to slower myopia progression in Chinese Uyghur schoolchildren.BMC public health · 2026Observational
- Longitudinal quantitative assessment of macular retinal and choroidal remodeling after trabeculectomy in chronic primary angle-closure glaucoma using ultra-widefield SS-OCTA.Scientific reports · 2025Observational
- Differences in macular structure and microvasculature between high myopia and non-high myopia.Frontiers in medicine · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
Purpose: The study aimed to compare interocular differences in choroidal thickness and circulation between the paired eyes of anisomyopic adults and to further investigate the potential connection between the choroid and myopia severity. Methods: A total of 120 eyes of 60 anisomyopic adults were included in this observational cross-sectional study. All patients underwent detailed ocular examinations, including spherical equivalent refraction (SER), axial length (AL), and other biometric parameters. Mean choroidal thickness (MCT), choriocapillaris blood flow area (CBFA), choroidal vessel volume (CVV), and choroidal vessel index (CVI) were measured over a 6 mm x 6 mm macular area using swept-source optical coherence tomography (SS-OCTA). Interocular differences in the abovementioned measurements between the paired eyes of the anisomyopic individuals were analyzed. Results: The mean SER was -5.98 ± 1.72 diopters (D) in the more myopic eyes and -3.38 ± 1.71 D in the less myopic eyes, while the mean interocular difference in SER was -2.60 ± 1.17 D. The more myopic eyes had lower values of MCT, CBFA, CVV, and CVI than the relatively less myopic fellow eyes (all Conclusion: Choroidal thickness and circulation were found to be reduced in the more myopic eyes of anisomyopic adults. We observed that the greater the interocular difference in SER, the lower the choroidal thickness and circulation, indicating that the choroid is impaired in individuals with myopia and is more likely to be compromised with severe myopia.
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