Evidence map›Paper›PMID 40761798›Full record

ArticleFrontiers in immunology2025

MetE: a promising protective antigen for tuberculosis vaccine development.

Salem Salman Almujri, Elena Stylianou, Annalisa Nicastri, Iman Satti, Marcellus Korompis, Shuailin Li, Christopher J De Voss, Marco Polo Peralta Alvarez, Rachel Tanner, Paulo J G Bettencourt and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Salem Salman AlmujriThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Elena StylianouThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Annalisa NicastriThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Iman SattiThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Marcellus KorompisThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Shuailin LiThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Christopher J De VossThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Marco Polo Peralta AlvarezThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Rachel TannerThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Paulo J G BettencourtThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Nicola TernetteThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Helen McShaneThe Jenner Institute, University of Oxford, Oxford, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Introduction: Tuberculosis (TB), caused by Methods: Using immunopeptidomics, we identified 64 and 80 unique mycobacterial antigens derived from BCG and MTB, respectively. We prioritised antigens based on HLA allele coverage through an immunoinformatics approach. Results: The candidates, Conclusion: Our findings highlight

Indexed as

Antigens, BacterialMycobacterium tuberculosisTuberculosisTuberculosis VaccinesVaccine DevelopmentAdjuvants, ImmunologicAnimalsCytokinesFemaleHumansMiceVaccines, DNAAdjuvants, ImmunologicAntigens, BacterialCytokinesTuberculosis VaccinesVaccines, DNAantigen discoveryHLA/MHCimmunoinformaticsimmunopeptidomicsmass spectrometrymycobacterium tuberculosistuberculosisvaccines

Identifiers

PMID40761798
PMCPMC12319054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.