ReviewFrontiers in cell and developmental biology2025
Research progress on the role of the NEIL family in cancer.
Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Molecular Context of ADAR-Mediated Editing of Coding RNA in Colorectal and Lung Cancers.International journal of molecular sciences · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is the primary cause of death worldwide. Cancer occurrence and progression are closely associated with DNA damage repair. DNA glycosylase were the first enzymes to initiate base excision repair, and the Nei-like DNA glycosylase (NEIL) family has attracted increasing attention as an important component of DNA glycosylases. Here, we introduce the role of the NEIL family in the malignant biological behaviors of cancer, including cell proliferation, chemoradiotherapy resistance, invasion and migration, apoptosis, and stemness. Mechanisms affecting the expression of the NEIL protein family range from the transcriptional level and mRNA editing to the level of post-translational modification. Additionally, we emphasize the different functions of the NEIL family in various malignancies and present useful information that supports the hypothesis that the NEIL family could be a potential target in the treatment and diagnosis of various cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.