One-Stage Primary Total Knee Arthroplasty as the Treatment of Acute Septic Arthritis of the Native Osteoarthritic Knee: Report of 3 Cases and Review of Literature.

Mohammad Mahdi Sarzaeem, Davood Feizi, Hamidreza Jamshidi Kouhsari, Farzad Amouzadeh Omrani, Ali Pourmojarab

Abstract readCase Reports

In one paragraph

Article in Arthroplasty today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Functional outcomes of one-stage arthroplasty for native septic knee arthritis: a matched case-control study versus primary osteoarthritis.Frontiers in cellular and infection microbiology · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Mahdi SarzaeemDepartment of Orthopaedic Surgery and Traumatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Davood FeiziDepartment of Orthopaedic Surgery and Traumatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Hamidreza Jamshidi KouhsariDepartment of Orthopaedic Surgery and Traumatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Farzad Amouzadeh OmraniDepartment of Orthopaedic Surgery and Traumatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Ali PourmojarabDepartment of Orthopaedic Surgery and Traumatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present three cases of acute septic arthritis in osteoarthritic knees managed with one-stage primary total knee arthroplasty and followed for 2 years. This approach, diverging from conventional staged protocols, combines thorough debridement, immediate biomechanical restoration, and extended antibiotic therapy. Patients exhibited significant symptomatic relief, functional recovery, and no recurrent infections. Literature supports the efficacy of single-stage revisions in chronic periprosthetic infections, yet its application to acute septic arthritis remains underexplored. Our findings highlight the importance of meticulous patient selection, considering host immunity, microbial virulence, and comorbidities. One-stage total knee arthroplasty offers a viable, streamlined alternative for well-selected patients, mitigating the morbidity of multiple surgeries and protracted recovery.

Indexed as

Infection managementJoint replacementOsteoarthritisSeptic arthritisSingle-stage surgeryTotal knee arthroplasty

Identifiers

PMID40761690

DOI10.1016/j.artd.2025.101777

PMCPMC12320547

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