Evidence map›Paper›PMID 40761674›Full record

ArticleClinical case reports2025

Platypnea-Orthodeoxia Syndrome Post-Pneumonectomy: A Case of Right-To-Left Shunting and Successful PFO Closure.

Cristian Castillo-Rodriguez, Dina Soliman, Michel Juarez, Sherif Roman, John Abdelmalek, Zhaunn Sly, Ankush Lahoti, Victor Test

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristian Castillo-RodriguezDepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USA.ORCID https://orcid.org/0000-0001-5210-2875
Dina SolimanDepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USA.ORCID https://orcid.org/0009-0005-9489-7641
Michel JuarezDepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USA.
Sherif RomanDivision of Cardiology Texas Tech University Health Sciences Center Lubbock Texas USA.
John AbdelmalekDivision of Cardiology Texas Tech University Health Sciences Center Lubbock Texas USA.
Zhaunn SlyDivision of Cardiology Texas Tech University Health Sciences Center Lubbock Texas USA.
Ankush LahotiDivision of Cardiology Texas Tech University Health Sciences Center Lubbock Texas USA.
Victor TestDivision of Pulmonary and Critical Care Texas Tech University Health Sciences Center Lubbock Texas USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platypnea-orthodeoxia syndrome is a rare disorder characterized by dyspnea (platypnea) and arterial desaturation (orthodeoxia) in the upright position, with symptom relief upon lying down. This syndrome is commonly associated with cardiac anomalies, particularly patent foramen ovale (PFO), where increased right atrial pressure facilitates right-to-left shunting, leading to hypoxemia. Other associated conditions include cirrhosis, pericardial effusion, and pneumonectomy. We present a 32-year-old female with a history of right pneumonectomy for invasive aspergillosis who presented with worsening dyspnea and a greater than 10% drop in SpO

Indexed as

atrial septal defectorthodeoxiapatent foramen ovaleplatypnea

Identifiers

PMID40761674
PMCPMC12318820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.