Evidence map›Paper›PMID 40761657›Full record

ArticleERJ open research2025

Spirometry at different Latin American altitudes: a Global Lung Function Initiative project.

Laura Gochicoa-Rangel, David Martínez-Briseño, Cole Bowerman, Sanja Stanojevic, Luciano Enrique Busi, Santiago C Arce, Mónica Gutiérrez-Clavería, Carlos E Rodríguez-Martínez, Carlos Aguirre-Franco, Ana Moya-Olivares and 8 more

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Laura Gochicoa-RangelDepartamento de Fisiología Respiratoria, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.
David Martínez-BriseñoLaboratorio de Investigación en Epidemiología e Infectología, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.
Cole BowermanMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0002-9871-281X
Sanja StanojevicDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.ORCID https://orcid.org/0000-0001-7931-8051
Luciano Enrique BusiUnidad de Neumonología, Hospital de Trelew, Trelew, Argentina.
Santiago C ArceLaboratorio de Función Pulmonar, Instituto de Investigaciones Médicas A. Lanari, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-2629-3262
Mónica Gutiérrez-ClaveríaDepartamento de Neumología Hospital Naval Almirante Nef Universidad de Valparaiso, Viña del Mar, Chile.
Carlos E Rodríguez-MartínezDepartment of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.
Carlos Aguirre-FrancoLaboratorio de Funcion Pulmonar, Fundación Neumológica Colombiana, Bogota, Colombia.ORCID https://orcid.org/0000-0001-9001-0613
Ana Moya-OlivaresSociedad Chilena de Neumología Pediátrica, Santiago, Chile.
Vanessa Vernaza-AlcedoDepartamento de Neumologia, Hospital del Niño Dr. José Renán Esquivel, Panama, Panama.
Nilda Luz Palma ChambillaColegio Médico Regional V de Arequipa, Arequipa, Peru.
Nelson Villca-AláCentro Respiratorio La Paz (CERELAP), La Paz, Bolivia.
Rosario Fernández-PlataLaboratorio de Investigación en Epidemiología e Infectología, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.
Rogelio Pérez-PadillaDepartamento de Investigación en Tabaquismo y EPOC, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico.
Carlos Guzmán-ValderrábanoLaboratorio de Función Respiratoria, Instituto de Desarrollo e Innovación en Fisiología Respiratoria, Mexico City, Mexico.
Marie Solange-CaussadeDepartamento Enfermedades Respiratorias Pediátricas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Luis Torre-BouscouletLaboratorio de Función Respiratoria, Instituto de Desarrollo e Innovación en Fisiología Respiratoria, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Approximately 20% of people in Latin America live more than 2500 m above sea level. In this ethnically and socioeconomically diverse population, it is challenging to differentiate the effects of altitude from population differences in lung function. The aim of the present study was to quantify the contribution of altitude on the variability in lung function measured by spirometry in Latin America. Methods: Data from healthy individuals living in nine cities across Latin America (from sea level to >2500 m above sea level) were collated. Results: A total 4480 subjects (3-94 years) were included. Average FEV Conclusion: For people living at altitude, existing approaches to interpreting spirometry measures may misclassify individuals.

Identifiers

PMID40761657
PMCPMC12320107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.