Evidence map›Paper›PMID 40761655›Full record

ArticleERJ open research2025

Top 10 priorities for chronic cough: Canadian James Lind Alliance Priority-Setting Partnership (CAN-COUGH).

Saif Samari, Ana Oliveira, Danica Brister, Elena Kum, Shawn D Aaron, Darryl Adamko, Anurag Bhalla, Christopher Carlsten, Maxime Cormier, Anne K Ellis and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Saif SamariDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Ana OliveiraRespiratory Research and Rehabilitation Laboratory (Lab3R), School of Health Sciences (ESSUA), University of Aveiro, Aveiro, Portugal.ORCID https://orcid.org/0000-0003-4516-6904
Danica BristerDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Elena KumDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Shawn D AaronOttawa Hospital Research Institute, Ottawa, ON, Canada.
Darryl AdamkoDepartment of Pediatrics, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Anurag BhallaDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Christopher CarlstenDivision of Respiratory Medicine, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0003-2455-6575
Maxime CormierDivision of Respiratory Medicine, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Anne K EllisDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Stephen K FieldDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Krystelle GodboutQuebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.
Paul HernandezDivision of Respirology, Department of Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Jeremy A HirotaDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Alan KaplanFamily Physician Airways Group of Canada, Markham, ON, Canada.
Tom KovesiDepartment of Pediatrics, University of Ottawa, Ottawa, ON, Canada.
Renata MancopesSwallowing Rehabilitation Research Laboratory, KITE Research Institute, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada.
Maria SedenoRESPIPLUS, Montreal, QC, Canada.ORCID https://orcid.org/0000-0001-7108-1512
Maeve SmithDivision of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Robert NewmanPatient partners.
Philip KingPatient partners.
Tiffany GallagherPatient partners.
Sarah ButsonCanadian Lung Association, Ottawa, ON, Canada.
Dina BrooksDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Imran SatiaDepartment of Medicine, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0003-4206-6000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic cough significantly impacts individuals' quality of life and poses challenges for healthcare providers due to limited licensed treatments, side effects of available medications and difficulty accessing nonpharmacological interventions. Understanding priorities for research, education and knowledge dissemination from the perspectives of individuals with chronic cough and healthcare providers can guide future efforts. This study aimed to identify these key priorities in Canada. Study design and methods: We conducted a cross-sectional study using the James Lind Alliance (JLA) method to set priorities. Chronic cough was identified as the healthcare problem. Participants rated items related to research, education and knowledge dissemination in an online survey using a seven-point Likert scale. Results of the survey were reviewed by the Canadian Thoracic Society's (CTS) multidisciplinary working group and patient partners who engaged in a face-to-face Priority-Setting Partnership, to establish a "Top 10" priorities list for chronic cough. Results: 74 individuals with chronic cough and 62 healthcare providers completed the scoping survey. The top-rated priorities included enhancing knowledge of existing treatments, developing new treatments and improving diagnostic testing. The final "Top 10" priorities list emphasised the need for developing infrastructure for evaluating new treatments, improving understanding of biological mechanisms and raising awareness among the public and policymakers. Conclusion: This is the first priority-setting project for chronic cough, highlighting key areas to address in research, education and dissemination. The identified priorities will serve as a foundation for future efforts to improve the management and care of individuals with chronic cough.

Identifiers

PMID40761655
PMCPMC12320103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.