ArticleFrontiers in neurology2025
Association between serum uric acid levels and white matter hyperintensities in patients with mild ischemic stroke.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to investigate the association between uric acid (SUA) level and white matter hyperintensities (WMH) in patients with mild ischemic stroke. Methods and results: This study retrospectively analyzed 290 patients with mild ischemic Stroke who were hospitalized at the Second Hospital of Hebei Medical University from March 2021 to January 2022. General clinical information and laboratory test results were collected. WMH was interpreted on MRI, and periventricular hyperintensity (PVH) and deep white matter hyperintensities (DWMH) were scored, respectively. According to the score of Fazekas, WMH was divided into two groups. Factors influencing WMH severity were analyzed, and the relationship between SUA and WMH was further explored. The results showed that the SUA of patients with moderate to severe DWMH was higher than that of patients with no or mild DWMH (345.10 ± 97.52 μmol/L vs. 317.99 ± 91.21 μmol/L, Conclusion: SUA is an independent risk factor for DWMH in patients, and there is no significant correlation between SUA level and PVH.
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