ReviewFrontiers in bioengineering and biotechnology2025
Advances in hyaluronic acid hydrogel for meniscus repair.
Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Temporal Hierarchy of Hydrogels and Orthobiologic Therapies for Knee Osteoarthritis.Gels (Basel, Switzerland) · 2026Review
- RNA-Seq of Gingival Fibroblasts Grown on Collagen Membranes and Hyaluronic Acid.Journal of functional biomaterials · 2026Article
- Integrated strategies in meniscus tissue engineering: from biomaterials to stem cell-driven regeneration.Frontiers in bioengineering and biotechnology · 2026Review
- Biomaterials and Tissue Engineering in Neurosurgery: Current Innovations and Future Directions.Biotech (Basel (Switzerland)) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The meniscus, an important fibrocartilaginous structure within the knee joint, plays essential roles in shock absorption, joint stabilization, and the optimization of mechanical force transmission. Meniscus injuries are common among athletes, middle-aged and elderly individuals, and those engaged in heavy physical labor. Both conservative and surgical treatments currently have limitations, making it difficult to achieve complete repair and functional restoration of meniscal tissue. In recent years, hyaluronic acid (HA) hydrogel has shown broad potential in meniscus repair due to its excellent biocompatibility and biodegradability. As a cell carrier, this material not only promotes cell migration, proliferation, and differentiation but also mimics the biomechanical properties of the meniscus, regulates the inflammatory environment, and facilitates angiogenesis, thereby creating favorable conditions for tissue regeneration. This review summarizes the mechanisms, current applications, and research advances of HA hydrogel in meniscus repair, aiming to provide new theoretical foundations and technical support for meniscus injury treatment and to promote clinical translation and development in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.