ArticleCardiovascular therapeutics2025
Eplerenone Inhibits Atrial Autonomic Nerve Remodeling in Atrial Fibrillation Through ERK1/2 MAPK Pathway.
Wei Xu, Cheng-Yuan Yu, Ding-Yu Wang, Qiang Gao, Song Zhang, Yun Zhang, Yue Yuan, Jing Shi, Yue Li, Guang-Zhong Liu and 1 more
Abstract read
In one paragraphArticle in Cardiovascular therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Cheng-Yuan YuDepartment of Geriatrics, Shenzhen People's Hospital (The First Affiliated Hospital, Southern University of Science and Technology; The Second Clinical Medical College, Jinan University), Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Center for Geriatrics, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0001-8653-1512 Ding-Yu WangDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Qiang GaoDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Song ZhangDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Yun ZhangDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Yue YuanDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Jing ShiDepartment of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Guang-Zhong LiuDepartment of Cardiology, Shenzhen People's Hospital (The First Affiliated Hospital, Southern University of Science and Technology; The Second Clinical Medical College, Jinan University), Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Center for Geriatrics, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0001-7009-9614 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Atrial autonomic nerve system (ANS) remodeling plays an important role in atrial fibrillation (AF). Mineralocorticoid receptor antagonists (MRAs) have been proved to be effective in preventing atrial structural remodeling. However, the effects of MRA on ANS remodeling in AF and the underlying mechanisms are still unknown.
Indexed as
Anti-Arrhythmia AgentsAtrial FibrillationAtrial RemodelingAutonomic Nervous SystemHeart AtriaMAP Kinase Signaling SystemMineralocorticoid Receptor AntagonistsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3SpironolactoneAldosteroneAnimalsCardiac Pacing, ArtificialCell LineDisease Models, AnimalEplerenoneAldosteroneAnti-Arrhythmia AgentsEplerenoneMineralocorticoid Receptor AntagonistsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Spironolactone
Identifiers
PMID40761415
PMCPMC12321439
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