Evidence map›Paper›PMID 40761356›Full record

ArticleFrontiers in nutrition2025

Effect of a specific food intervention with Tamogitake mushroom, Moringa leaves, or rice bran on intestinal microbiota and cognitive function in elderly Japanese.

Kouta Hatayama, Kanako Kono, Kana Okuma, Hiroaki Masuyama

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kouta HatayamaSymbiosis Solutions, Inc., Tokyo, Japan.
Kanako KonoSymbiosis Solutions, Inc., Tokyo, Japan.
Kana OkumaSymbiosis Solutions, Inc., Tokyo, Japan.
Hiroaki MasuyamaSymbiosis Solutions, Inc., Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The large number of elderly patients with dementia and mild cognitive impairment with cognitive decline in Japan has become a social problem. In this study, a food intervention study was conducted to test whether a food intervention approach targeting intestinal microbiota can improve cognitive function in elderly Japanese individuals. Methods: Japanese participants (144 males and 87 females) aged 60-79 years were assigned to one of the test food groups: Tamogitake mushroom ( Results: The participants were divided into responders (improved cognitive function) and non-responders (no improvement) within each sex group. Responders exhibited variations in intestinal bacteria belonging to specific taxa, including Conclusion: Food intervention approaches targeting the intestinal microbiota could lead to innovative solutions for improving cognitive function in the elderly.

Indexed as

cognitive functiondementiaintestinal microbiotaJapanmild cognitive impairmentMoringarice branTamogitake

Identifiers

PMID40761356
PMCPMC12320749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.