Evidence map›Paper›PMID 40761329›Full record

ArticleACG case reports journal2025

Cholestatic Drug-Induced Liver Injury From Rad-140 Successfully Treated With Corticosteroids.

Bilal Niazi, Bill Quach, Kurt Fisher, Thoetchai Peeraphatdit

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bilal NiaziDepartment of Gastroenterology and Hepatology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Bill QuachDepartment of Gastroenterology and Hepatology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Kurt FisherDepartment of Pathology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Thoetchai PeeraphatditDepartment of Gastroenterology and Hepatology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective androgen receptor modulators (SARMs) are anabolic compounds that modulate androgen activity. They have been increasingly used in supplements to enhance performance and muscle growth despite not being Food and Drug Administration approved. Their use has been associated with a cholestatic pattern of liver injury similar to that seen by anabolic androgens. Treatment is primarily supportive with drug cessation and cholestasis can take weeks to months to normalize. We present an atypical case of prolonged cholestasis caused by the readily available selective androgen receptor modulator called RAD-140 that was successfully managed with corticosteroids.

Indexed as

cholestatic DILIprolonged cholestasisSARM

Identifiers

PMID40761329
PMCPMC12321445

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.