ReviewFrontiers in oncology2025
Fertility preservation and assisted reproductive strategies in endometrial cancer patients with lynch syndrome.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Advances in the application of assisted reproductive technology in fertility preservation for female patients with malignant tumours of the reproductive systems.Annals of medicine · 2026Review
- Oncological and reproductive outcomes following fertility-preserving treatment in mismatch repair-deficient endometrial cancer or atypical endometrial hyperplasia.BMC women's health · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with LS-EC can be treated with progestin-based fertility-sparing treatment under close monitoring, and pregnancy is recommended as soon as possible after complete remission (CR) of the disease, with assisted reproduction, supplemented by PGT-M, to minimize the probability of inheritance of the disease in the offspring. Radical surgery for endometrial cancer is recommended as soon as possible after completion of childbearing to minimize recurrence. The role of assisted reproductive technologies (ART) and preimplantation genetic testing for monogenic disorders (PGT-M) was explored. For patients achieving CR, early initiation of ART, especially IVF with frozen-thawed embryo transfer (FET), was associated with improved reproductive outcomes. PGT-M proved valuable in preventing the transmission of pathogenic MMR variants to offspring. Early use of ART and integration of PGT-M are critical for maximizing reproductive success while minimizing oncologic and hereditary risks.
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