Evidence map›Paper›PMID 40761139›Full record

ArticleJournal of pineal research2025

Circadian Rhythm Timing and Associations With Sleep Symptoms in People With Insomnia.

Hannah Scott, Nicole Lovato, Maria Comas, Delwyn Bartlett, Ronald R Grunstein, Leon Lack, Christopher J Gordon

Abstract read
In one paragraph

Article in Journal of pineal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hannah ScottFlinders Health and Medical Research Institute: Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, Australia.ORCID https://orcid.org/0000-0002-0707-8068
Nicole LovatoFlinders Health and Medical Research Institute: Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Maria ComasSleep Unit, Araba University Hospital, Vitoria-Gasteiz, Spain.ORCID https://orcid.org/0000-0002-1368-0274
Delwyn BartlettCIRUS Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, Australia.
Ronald R GrunsteinCIRUS Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, Australia.
Leon LackFlinders Health and Medical Research Institute: Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, Australia.ORCID https://orcid.org/0000-0002-8505-5873
Christopher J GordonCIRUS Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, Australia.

Funding

The research was supported by the Co-Operative Research Centre (CRC) for Alertness, Safety and Productivity. The Alertness CRC receives funds from the Commonwealth of Australia Department of Industry and industry/NGO participants. N.L. was supported with funding from the Alertness CRC. R.R.G. was a CRC Program Leader and C.J.G. was a CRC Project Leader. R.R.G. was funded by a National Health and Medical Council of Australia Senior Principal Research Fellowship (1106974).
6 · The paper itself

Abstract

Circadian rhythmicity plays a crucial role in regulating sleep timing and continuity, but it may be altered in people with insomnia. This study tested whether dim-light melatonin onset (DLMO) timing is associated with sleep difficulties in insomnia. In total, 128 people diagnosed with insomnia disorder were recruited. Participants completed daily sleep diaries and wore an actigraph for up to 14 days before the laboratory visit to estimate mean sleep continuity (e.g., sleep latency, sleep duration) and sleep timing (sleep onset time and wake time from diaries, bedtime from diaries and actigraphy). After a sleep study, participants underwent salivary melatonin collection to estimate DLMO on the following night. Regressions and analyses of variances on tertile groups tested associations between DLMO (clock times and phase angle differences between DLMO and sleep timing) and sleep continuity and timing. There were associations between DLMO and sleep timing, r

Indexed as

Circadian RhythmSleepSleep Initiation and Maintenance DisordersActigraphyAdultAgedFemaleHumansMaleMelatoninMiddle AgedMelatoninactigraphydifficulties initiating and maintaining sleepinsomniamelatoninsleep diarysleep health

Identifiers

PMID40761139
PMCPMC12322714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.