Evidence map›Paper›PMID 40761111›Full record

ReviewCurrent drug research reviews2025

Reviewing the Therapeutic Potential of Plant-based Natural Products against Multidrug-resistant Bacteria (MDR).

Ragini Pandey, Puneet Gupta

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug research reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ragini PandeyDepartment of Pharmacy, Amity Institute of Pharmacy, Amity University, Uttar Pradesh, Sector 125, Noida, 201313, India.
Puneet GuptaDepartment of Pharmacy, Amity Institute of Pharmacy, Amity University, Uttar Pradesh, Sector 125, Noida, 201313, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global health of individuals is severely threatened by drug-resistant microorganisms. Existing antibiotics available in the market, such as penicillin, cephalosporins, new β- lactams, aminoglycosides, macrolides, lincomycin, and quinolones, are losing their effectiveness due to overuse and inappropriate prescribing, among other factors. This situation underscores the urgent need to develop new antimicrobial agents. In response to this challenge, attention has been directed towards natural products derived from plants, which have been utilized for their medicinal benefits over an extended period. Various studies have demonstrated that plant-based natural products exhibit antibacterial action against multidrug-resistant (MDR) bacteria, making them potential candidates for the development of novel antimicrobial medicines. Plants belonging to classes, such as alkaloids, organosulfur compounds, terpenoids, coumarin, and polyphenols have been found to possess antimicrobial properties. This paper reviews the antimicrobial activity of plant-based natural products, whether used alone or in combination with conventional antibiotics. Additionally, the paper explores their mechanisms against drugresistant bacteria, the potential development of resistance against them, their current role in medicine, and their future perspectives.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiological ProductsDrug Resistance, Multiple, BacterialAnimalsBacteriaHumansAnti-Bacterial AgentsBiological Productsantimicrobial agentsAntimicrobial resistancemulti drug resistance.natural productspathogenic microbesplant secondary metabolite

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.