Evidence map›Paper›PMID 40761110›Full record

ReviewCurrent drug research reviews2025

Effects of Cannabis Exposure on Adolescent Health and Development: A Narrative Review.

Ruixuan Li, Feng Tao

Abstract readReview
In one paragraph

Review in Current drug research reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ruixuan LiThe Hockaday School, Dallas, Texas, USA.
Feng TaoDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescence is an immature but adventurous time period of exploration. Due to rapid developments of the brain with unbalanced release of neurotransmitters, adolescents are prone to impulsivity that may carry out potentially dangerous behaviors. According to the Centers for Disease Control and Prevention, more than one-third of high school students have reported the use of cannabis or marijuana in 2019, and the trend has not declined since. Previous studies have shown that cannabis not only affects cognitive and social behaviors, but also produces psychological responses to stress. In this review, we have summarized recent studies on cannabis- produced effects during the unique period of adolescent development, and we have also briefly discussed the legalization of cannabis. Though there are slight differences between cannabis and marijuana, the major active component of them is tetrahydrocannabinol. We have used the term "cannabis" in this review. Cannabis use in adolescents causes structural and functional changes in the brain, increasing the probability of depression, which is also associated with other illicit substance use, and impairs education achievement. Given that cannabis use can cause detrimental harm to adolescents, it is suggested that adolescents should generally avoid using cannabis in a recreational manner. More preclinical and clinical studies are needed to provide detailed information for evidence-based decisions.

Indexed as

Adolescent BehaviorAdolescent DevelopmentAdolescent HealthCannabisMarijuana SmokingMarijuana UseAdolescentBrainHumansAdolescencebraincannabinoid receptorcannabislegalization.substance use

Identifiers

PMID40761110
PMCPMC12376134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.