ArticleObstetrics & gynecology science2025
A knowledge, attitudes, and practices study on BRCA mutations among family members of women diagnosed with epithelial ovarian or fallopian tube cancer.
Article in Obstetrics & gynecology science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBReast CAncer (BRCA) gene mutations increase the risk of epithelial ovarian and fallopian tube cancers. Genetic counseling and screening play a crucial role in identifying individuals at risk. Assessing knowledge, attitudes, and practices (KAP) related to BRCA mutations among family members of affected individuals can assist in early detection and preventive strategies. This study aims to evaluate KAP among family members of patients with these cancers to identify gaps and improve awareness.
methodsA cross-sectional survey was conducted between March and November 2024, involving 215 participants with a family history of epithelial ovarian or fallopian tube cancer. Data were collected through structured interviews.
resultsThe mean age of participants was 47.3 years; 42.8% were single and 44.2% were nulliparous. Most participants (65.6%) had one affected relative, with 86.5% being first-degree relatives. Only 16.3% had heard of BRCA mutations and 18.2% were aware of their association with ovarian cancer. The most commonly recognized ovarian cancer symptom was abdominal swelling. The highest mean KAP score was associated with the belief that regular pelvic examinations should be performed. Multivariate analysis identified independent factors influencing the desire for BRCA screening, including an attitude score of ≥25 (adjusted odds ratio [AOR], 12.638; P<0.001), follow-up duration of >5 years (AOR, 2.504; P=0.016), and ongoing or ineffective treatment (AOR, 4.303; P<0.001).
conclusionSubstantial gaps in KAP regarding BRCA mutations persist among family members of affected individuals. Targeted educational interventions and healthcare initiatives are essential to enhance awareness and support informed decision-making in high-risk populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.