Evidence map›Paper›PMID 40760964›Full record

ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2025

Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients.

Min Li, Wanyi Xie, Qingrui Lv, Meitang He, Hanhong Zou, Miaoying Hong, Hanyan Pang, Jingchao Cai, Jianshuang Shi, Wenhao Huang

Expression of concernAbstract read
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In one paragraph

Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Min LiThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Wanyi XieThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qingrui LvThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Meitang HeThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Hanhong ZouThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Miaoying HongDepartment of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Hanyan PangThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jingchao CaiThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jianshuang ShiThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Wenhao HuangThe Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAcupoint thread embedding treatment (ATET) is a traditional therapeutic approach used in stroke rehabilitation.ObjectiveTo explore the application of ATET in combination with modern medical technology, examining its effects on neurological function and key serum biomarkers in stroke patients.MethodsA total of 108 stroke patients were randomly assigned to ATE treatment group (n = 52) and Control Group (n = 56). Various parameters including baseline characteristics, levels of inflammatory markers, macrophage efferocytosis-related factors, the National Institutes of Health Stroke Scale (NIHSS) scores, therapeutic efficacy, and adverse events were assessed and compared between the two groups.ResultsA significant improvement in NIHSS scores was observed in the treatment group compared to the control group. Additionally, serum levels of SIRT1, HIF-1α, and macrophage efferocytosis-related factors were significantly altered, suggesting that ATET may influence biological pathways involved in stroke recovery.ConclusionThe application of ATET, supported by advanced diagnostic technologies, shows promising effects in stroke rehabilitation. This study highlights the potential for integrating traditional therapies with modern medicine to improve clinical outcomes in stroke patients.

Indexed as

Acupoint thread embedding treatmentHIF-1αmacrophage efferocytosis-related factorsNIHSS scoreSIRT1stroke

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.