Evidence map›Paper›PMID 40760928›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Preoperative Care Clinic Improves Survival for Patients Undergoing Free-Flap Reconstruction.

Randall J Harley, Stephen A Esper, Tracy Z Cheng, Soukaina Eljamri, Preetha Velu, Mario G Solari, Shaum S Sridharan, Mark Kubik, Seungwon Kim

Abstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Randall J HarleyDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-8519-5366
Stephen A EsperDepartment of Anesthesia, Center of Perioperative Care, UPMC, Pittsburgh, Pennsylvania, USA.
Tracy Z ChengDepartment of Otolaryngology and Head and Neck Surgery, UPMC, Pittsburgh, Pennsylvania, USA.
Soukaina EljamriSchool of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Preetha VeluSchool of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Mario G SolariDepartment of Plastic Surgery, UPMC, Pittsburgh, Pennsylvania, USA.
Shaum S SridharanDepartment of Otolaryngology and Head and Neck Surgery, UPMC, Pittsburgh, Pennsylvania, USA.
Mark KubikDepartment of Otolaryngology and Head and Neck Surgery, UPMC, Pittsburgh, Pennsylvania, USA.
Seungwon KimDepartment of Otolaryngology and Head and Neck Surgery, UPMC, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to evaluate whether perioperative care improves postoperative outcomes for head and neck reconstruction patients with preexisting health conditions. STUDY

designRetrospective cohort study.

settingSingle tertiary academic center between 2013 and 2021.

methodsThis study included adult patients who underwent free-flap reconstruction for head and neck cancer. Patients who received perioperative care were compared with patients who received our institution's standard of care. Comorbid health conditions were measured using the Charlson comorbidity index (CCI) excluding solid tumors. Primary outcomes were major and minor complications, length of hospital stay (LOS), days in intensive care unit (ICU), discharge to acute/subacute facility, hospital-free days, and overall survival (OS). Interaction models were specified to evaluate the impact of preoperative care with respect to CCI.

resultsOf the 148 patients included, 83 received perioperative care and 65 received institutional standard of care (mean [SD]: age, 62.1 [10.8]; male, 100 [67.6%]; CCI

conclusionPerioperative care provides a robust benefit for patients with medical comorbidities undergoing head and neck reconstruction, but this effect incrementally decreases for healthier patients.

Indexed as

Free Tissue FlapsHead and Neck NeoplasmsPlastic Surgery ProceduresPreoperative CareAgedFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSurvival Ratefree‐flap reconstructionhead and neck cancerhospital‐free dayslength of hospital staypreoperative carequality improvementsquamous cell carcinomasurvival

Identifiers

PMID40760928
PMCPMC12574647

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.