ArticleBrain and behavior2025
Improving Treatment Adherence in Youths With Multidrug-Resistant Tuberculosis With Psychosocial Intervention.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches.Advances in respiratory medicine · 2026Article
- Factors Influencing Adherence to All-Oral Short-Course Treatment for DR-TB and Establishment of a Predictive Model.Infection and drug resistance · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
introductionMultidrug-resistant tuberculosis (MDR-TB) deeply impacts the well-being of adolescents and young adults (AYA), resulting in poor treatment adherence. Identifying psychosocial challenges and preferred interventions is essential to enhance treatment adherence and outcomes in this unique group.
methodsThis was a mixed-method study where participants aged between 15 and 24 years, diagnosed with MDR-TB, were recruited for in-depth interviews and a semi-structured questionnaire.
resultsThe individual-level psychosocial challenges included mental stress, suicidal ideation, reluctance to continue medication, perceived and experienced stigma, and socio-economic burdens. Health system-related challenges encompassed delayed diagnosis, drug stockouts, and negative experiences with Health Care Providers (HCPs). Among 75 participants, the median age was 20.5 years, with 57% (n = 41) females, 85% (n = 62) single, and a median treatment duration of 8 months at the interview. Seventy-two percent (n = 54) of the participants reported psychological issues such as irritation, loneliness, anxiety, sleep disorder, suicidal ideation, and stigma. Individual-level interventions were preferred by 61% (n = 46) of participants, including social media, deep breathing, and exercise training.
conclusionsTo enhance results in MDR-TB, it is crucial to develop and assess personalized psychosocial interventions with tailored adjustments to tackle the psychosocial obstacles encountered by adolescents and young adults with MDR-TB.
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Registered trials
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