ArticleInternational journal of retina and vitreous2025
Changes in retinal and choroidal thickness after carotid endarterectomy: a systematic review.
Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Visual electrophysiology in carotid endarterectomy: a systematic review.International journal of retina and vitreous · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarotid endarterectomy is a well-established procedure for enhancing cerebral perfusion in patients with internal carotid artery stenosis. As a multifactorial disease, carotid stenosis can have ocular implications, potentially affecting retinal and choroidal perfusion and contributing to visual dysfunction. This systematic review aims to evaluate changes in choroidal and retinal thickness after unilateral carotid endarterectomy, providing insight into the impact of the procedure on ocular perfusion.
methodsA comprehensive search was performed across PubMed, Scopus, and Web of Science up to July 2024, without restrictions on language or publication date. The inclusion criteria included original studies assessing retinal or choroidal thickness via optical coherence tomography before and after carotid endarterectomy in adults. Additional manual searches of reference lists and citation tracking were employed to ensure completeness. Study quality was appraised via the NHLBI tool for observational studies.
resultsSix prospective observational studies involving 269 patients were included. Findings on choroidal thickness changes after carotid endarterectomy are heterogeneous. While two studies reported significant postoperative Choroidal Thickness increases-one within a week and another at three months-other studies reported no significant changes. One study suggested that higher degrees of carotid stenosis may blunt early Choroidal Thickness response. Retinal measurements were less consistently assessed; among the three studies that evaluated retinal nerve fibre layer and ganglion cell complex thickness, no consistent postoperative changes were observed. Overall, variability in study designs, Optical Coherence Tomography protocols, and follow-up durations limits comparability, precluding meta-analysis.
conclusionsThis review highlights a potential association between carotid endarterectomy and improved ocular perfusion, as reflected by changes in choroidal thickness. However, inconsistencies across studies and limited data on retinal structural outcomes underscore the complexity of this relationship. These findings emphasize the need for larger, standardized studies to clarify the impact of carotid revascularization on the ocular microvasculature and guide future clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.