Evidence map›Paper›PMID 40760649›Full record

ArticleBMC geriatrics2025

Analysis of risk-factors associated with hospital-acquired pneumonia in patients with alzheimer's disease based on gender differences.

Wei Chen, Yanan Chen, Qin Tang, Di Kong, Min Xu, Yan Yang, Qiwen Li, Mi Yang

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Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Wei ChenDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Yanan ChenDepartment of Infection Management, the First People's Hospital of Lianyungang, Lianyungang, 222061, Jiangsu, P. R. China.
Qin TangDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Di KongDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Min XuDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Yan YangDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Qiwen LiDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China.
Mi YangDepartment of Laboratory, Science Research and Education, Pharmacy and Hospital Infection Management, The Fourth People's Hospital of Chengdu, No.8 Huli-West 1st-Alley, Jinniu District, Chengdu, 610036, China. 565136170@qq.com.

Funding

Chengdu Science and Technology Bureau 2022-YF05-01867-SNHealth Commission of Chengdu 2022172Health Commission of Chengdu 2024141Health Commission of Sichuan Province 24CXTD11Science and Technology Department of Sichuan Province 2024ZYD0039Sichuan medical association S23012Sichuan Medical Association SYYXHPT202420The National Natural Science Foundation of China 62373079
6 · The paper itself

Abstract

backgroundPneumonia is an important cause of death in patients with Alzheimer's disease (AD), and understanding the factors associated with hospital-acquired pneumonia (HAP) is essential for preventing the development of HAP in AD patients. This study aimed to elucidate the specific risk factors related to HAP in AD patients based on gender differences.

methodsA total of 1066 patients with Alzheimer's disease (483 males, 583 females), who were admitted to a large psychiatric hospital for the first time between 2013 and 2023, were included in the study. The association between HAP and patients' personal characteristics, medication use and blood test results among genders was analysed. Finally, binary logistic regression was used to identify the independent risk factors for men and women.

resultsThe infection rate of HAP in male AD patients was significantly higher than that in females, at 41.8% and 23.3%, respectively (χ

conclusionThis study suggests that older AD patients are more susceptible to HAP; the infection rate of HAP in male patients with Alzheimer's disease is higher than that in females, and there are differences in the factors associated with the occurrence of HAP between male and female patients. It is suggested that prevention and treatment strategies for hospital-acquired pneumonia in individuals with Alzheimer's disease could consider age and gender differences.

Indexed as

Alzheimer DiseaseCross InfectionHealthcare-Associated PneumoniaAgedAged, 80 and overFemaleHumansMaleRisk FactorsSex FactorsAlzheimer's diseaseBlood biomarkersClinical medicationGender differencesHospital acquired pneumonia

Identifiers

PMID40760649
PMCPMC12323024

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