Evidence map›Paper›PMID 40760478›Full record

ArticleBMC medical informatics and decision making2025

Evaluation of large language models in patient education and clinical decision support for rotator cuff injury: a two-phase benchmarking study.

Yi-Lin Wang, Li-Chao Tian, Jing-Yuan Meng, Jie-Chao Zhang, Zhi-Xing Nie, Wen-Rui Wei, Dao-Fang Ding, Xiao-Ye Tang, Qian Zhang, Yong He

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yi-Lin Wang *Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Li-Chao Tian *Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Jing-Yuan MengGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Jie-Chao ZhangGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Zhi-Xing NieGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Wen-Rui WeiGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China.
Dao-Fang DingShanghai University of Traditional Chinese Medicine, No.1200, Cailun Road, Shanghai, 201203, China.
Xiao-Ye TangShanghai University of Traditional Chinese Medicine, No.1200, Cailun Road, Shanghai, 201203, China.
Qian ZhangDepartment of Orthopedics, Wuxi No 9. People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China.
Yong HeGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, NO.1508, Yan'an West Road, Shanghai, 200052, China. hernshall@qq.com.

Funding

Scientific and Technological Innovation Action Plan Medical Innovation Research Project of Shanghai Science and Technology Committee Shanghai 21Y11911400
6 · The paper itself

Abstract

objectiveThis study evaluates the accuracy of ChatGPT-4o, ChatGPT-o1, Gemini, and ERNIE Bot in answering rotator cuff injury questions and responding to patients. Results show Gemini excels in accuracy, while ChatGPT-4o performs better in patient interactions.

methodsPhase 1: Four LLM chatbots answered physician test questions on rotator cuff injuries, interacting with patients and students. Their performance was assessed for accuracy and clarity across 108 multiple-choice and 20 clinical questions. Phase 2: Twenty patients questioned the top two chatbots (ChatGPT-4o, Gemini), with responses rated for satisfaction and readability. Three physicians evaluated accuracy, usefulness, safety, and completeness using a 5-point Likert scale. Statistical analyses and plotting used IBM SPSS 29.0.1.0 and Prism 10; Friedman test compared evaluation and readability scores among chatbots with Bonferroni-corrected pairwise comparisons, Mann-Whitney U test compared ChatGPT-4o versus Gemini; statistical significance at p < 0.05.

resultsGemini achieved the highest average accuracy. In the second part, Gemini showed the highest proficiency in answering rotator cuff injury-related queries (accuracy: 4.70; completeness: 4.72; readability: 4.70; usefulness: 4.61; safety: 4.70, post hoc Dunnett test, p < 0.05). Additionally, 20 rotator cuff injury patients questioned the top two models from Phase 1 (ChatGPT-4o and Gemini). ChatGPT-4o had the highest reading difficulty score (14.22, post hoc Dunnett test, p < 0.05), suggesting a middle school reading level or above. Statistical analysis showed significant differences in patient satisfaction (4.52 vs. 3.76, p < 0.001) and readability (4.35 vs. 4.23). Orthopedic surgeons rated ChatGPT-4o higher in accuracy, completeness, readability, usefulness, and safety (all p < 0.05), outperforming Gemini in all aspects.

conclusionThe study found that LLMs, particularly ChatGPT-4o and Gemini, excelled in understanding rotator cuff injury-related knowledge and responding to patients, showing strong potential for further development.

Indexed as

BenchmarkingDecision Support Systems, ClinicalLanguagePatient Education as TopicRotator Cuff InjuriesAdultComprehensionFemaleHumansLarge Language ModelsMaleMiddle AgedLarge language modelPatient educationReal world interviewRotator cuff injury

Identifiers

PMID40760478
PMCPMC12323112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.