Evidence map›Paper›PMID 40760387›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Early outcomes of contaminated midline incisional hernia repair with mesh suture.

Megan M Perez, Taaha Hassan, Mehul Mittal, May Li, Kazimir Bagdady, Paige N Hackenberger, Gregory A Dumanian, Michael Shapiro

Abstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Megan M PerezDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Taaha HassanDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Mehul MittalDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
May LiDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Kazimir BagdadyDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Paige N HackenbergerDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Gregory A DumanianDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA.
Michael ShapiroDepartment of Surgery, Northwestern Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2320, Chicago, IL, 60611, USA. mshapiro@nm.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMesh suture is a novel reinforcement construct designed to provide enhanced mechanical support during midline fascial closure in comparison to conventional sutures while minimizing tissue dissection and foreign body burden in comparison to use of a planar mesh. Its use in contaminated fields remains understudied. This study evaluates the early clinical outcomes following mesh suture closure in clean-contaminated and contaminated incisional hernia repairs.

methodsA retrospective review was conducted of patients undergoing incisional hernia repair with mesh suture closure between January 2023 and July 2024 across an academic health system. Eligible patients had clean-contaminated or contaminated wounds and underwent mesh suture implantation without planar mesh. Data included demographics, operative details, surgical site infections (SSI), surgical site occurrences (SSO), reoperations, readmissions, and hernia recurrence. Hernia recurrence-free survival was estimated using Kaplan-Meier analysis. Major complications were defined as surgical complication or reoperation within 90 days.

resultsFifty-one patients were included, with repairs performed by 22 surgeons. Most patients (62.7%) had clean-contaminated wounds. Anterior component separation was performed in 25.5% of cases. The 90-day SSI rate was 15.7%, with five patients requiring procedural intervention. The 90-day SSO rate was 23.5% and included one enterocutaneous fistula that resolved without surgical intervention. Readmission occurred in 27.4% of patients, and 9.8% underwent reoperation. Four hernia recurrences were observed (8.2%), with a 12-month recurrence-free survival of 91% and a mean recurrence-free survival of 17.3 months (95% CI: 16.5-18.1). Presence of a stoma was significantly associated with major complications (p = 0.041).

conclusionMesh suture closure was technically feasible across diverse surgical settings and demonstrated encouraging SSI and SSO rates as compared to conventional suture only and planar mesh-based repairs as reported in the literature. These findings support further investigation in prospective, comparative studies to assess long-term durability and comparative effectiveness.

Indexed as

HerniorrhaphyIncisional HerniaSurgical MeshSurgical Wound InfectionSuture TechniquesAgedFemaleHumansMaleMiddle AgedRecurrenceReoperationRetrospective StudiesSuturesTreatment OutcomeContaminated hernia repairIncisional herniaMesh repairRecurrenceSuture repairVentral hernia

Identifiers

PMID40760387
PMCPMC12321942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.