Evidence map›Paper›PMID 40760385›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2025

Timing of invasive strategy in patients with non-ST segment elevation acute myocardial infarction: A nationwide retrospective cohort analysis.

Cyril Camaro, Marijke J C Timmermans, Judith A van Erkelens, Chantal van Tilburg, Jan Reitsma, Dennis van Veghel, Karin E Arkenbout, Peter Danse

Abstract read
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Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Advancing cardiovascular care-key insights from the Netherlands Heart Journal 2025.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cyril CamaroDepartment of Cardiology, Radboud University Medical Centre, Nijmegen, The Netherlands. cyril.camaro@radboudumc.nl.ORCID http://orcid.org/0000-0001-6170-8318
Marijke J C TimmermansNetherlands Heart Registration, Utrecht, The Netherlands.
Judith A van ErkelensDutch Business Intelligence Centre for Health Care (VEKTIS), Zeist, The Netherlands.
Chantal van TilburgDutch Business Intelligence Centre for Health Care (VEKTIS), Zeist, The Netherlands.
Jan ReitsmaDutch Association of Health Insurers (ZN), Zeist, The Netherlands.
Dennis van VeghelNetherlands Heart Registration, Utrecht, The Netherlands.
Karin E ArkenboutDepartment of Cardiology, Tergooi Medical Centre, Hilversum, The Netherlands.
Peter DanseDepartment of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Dutch ACS working group endorses a delayed invasive approach for non-ST segment elevation myocardial infarction (NSTEMI) patients as safe and acceptable. We analysed the timing of invasive coronary angiography (ICA) and percutaneous coronary intervention (PCI) for all patients admitted with NSTEMI.

methodsFor this retrospective observational cohort study initiated by the Netherlands Heart Registration, we extracted Dutch medical claims and diagnosis codes for all NSTEMI patients who underwent PCI. Primary outcome was the time from hospital admission to ICA and PCI in patients admitted to PCI and non-PCI centres. Secondary analyses included the time from ICA to PCI and variation among individual PCI centres.

resultsA total of 36,573 NSTEMI patients (median age 68 years, 30% female) were included in the analysis. 24,857 patients (68%) were admitted to a hospital with PCI facilities (n = 30) and 11,716 patients (32%) to a hospital without PCI on site (n = 42). ICA was performed < 3 days (72 h) in 33,476 patients (92%). For patients admitted in PCI centres ICA was performed < 3 days in 94% (n = 23,328), median 0 days (IQR 0-1) vs 87% (n = 10,148), median 1 day (IQR 1-2) in non-PCI centres. The longest delay (median 3 days; IQR 2-5) between ICA and PCI occurred in patients first admitted to non-PCI centres and transferred after local ICA.

conclusionsICA within three days is achieved in a very high percentage of patients in both PCI and non-PCI centres. A clearly larger percentage receives PCI within three days when directly admitted to a PCI centre.

Indexed as

ACS guidelinesNational claims data, time to ICANon-ST segment elevation myocardial infarction, invasive coronary angiographyPercutaneous coronary interventionTime to PCI, length of stay

Identifiers

PMID40760385
PMCPMC12364789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.