ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025
Differential susceptibility of Streptococcus dentisani to dental surfaces: An atomic force microscopy study.
Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGiven frequent dental restorations, understanding the interactions of probiotic Streptococcus dentisani with enamel and dental materials is key, in contrast to the well-studied Streptococcus mutans. This knowledge is vital for the potential applications in promoting oral health of S. dentisani.
objectiveThis study aims to evaluate and compare S. mutans and S. dentisani initial adhesion, proliferation, and colonization on dental enamel and commonly used dental materials: nickel-chromium alloy, porcelain, lithium disilicate, autocured, and thermocured acrylics, using atomic force microscopy (AFM).
methodsThe study utilized S. mutans ATCC 35665 and S. dentisani CECT 7746 cultured in brain-heart infusion (BHI) broth. The dental substrates used consisted of enamel obtained from healthy unerupted third molars, nickel-chromium alloy (Ni-Cr), porcelain, lithium disilicate, and both autocured and thermocured acrylics. All simples were cut into 1 cm pieces and subsequently mounted for the AFM analysis. Bacterial suspensions were incubated on these surfaces for 24 h. Surface topography and bacterial adhesion, proliferation, and colonization were analyzed using AFM in contact mode. Roughness parameters (R
resultsAtomic force microscopy analysis revealed that after a 24-h incubation, S. mutans demonstrated a superior capacity to adhere, proliferate, and colonize all tested substrates compared to S. dentisani. Streptococcus dentisani was found to be more susceptible to the bactericidal effects of the materials. Notably, porcelain and lithium disilicate surfaces exhibited strong antimicrobial activity. On porcelain, no intact S. dentisani cells were observed, only bacterial debris. Similarly, lithium disilicate showed evidence of bacterial decomposition for both strains, suggesting a potent bactericidal effect.
conclusionFor the first time, our data revealed that S. dentisani exhibited a reduced capacity for dental surface adhesion, proliferation, and colonization across all tested substrates, compared to S. mutans.
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